The effect of daily doses of 0.1 mg 3,3',5-triiodothyronine (T3) kg for three consecutive days on hepatic O2 uptake was studied in the isolated perfused rat liver, in the absence and presence of the antioxidants desferrioxamine ...

Oxygen uptake by erythrocytes exposed to t‐butyl hydroperoxide (t‐BHP) exhibited an induction period. The rate of oxygen consumption can be reduced by antioxidants and blood plasma. The induction time was not appreciably ...

The effect of hyperthyroidism on liver glutathione (GSH) metabolism was studied in fed rats after the administration of 0.1 mg T3/kg body wt, for 1-3 consecutive days. T3-calorigenesis resulted in elevated rates of ...

The role of Kupffer cells in the hepatocellular injury and oxidative stress induced by lindane (20 mg/kg; 24h) in hyperthyroid rats (daily doses of 0.1 mg L-3,3′,5-triio-dothyronine (T3)/kg for three consecutive days) was ...

Objectives: Kupffer cells, liver macrophages involved in immunomodulation, phagocytosis, and biochemical attack, can induce cytotoxicity and inflammation when their activity is exacerbated. The aim of this study was to ...

Hyperthyroidism enhances the prooxidant activity of the liver by elevating superoxide radical and/or hydrogen peroxide generation in microsomal, mitochondrial, and peroxisomal fractions, with an increased respiratory burst ...

Acetaldehyde administration (0.3 g/kg) to rats fasted overnight induces a reduction in liver reduced glutathione (GSH) content and stimulates lipid peroxidation. An additive effect in the decrease in liver GSH is observed ...

Recently, we demonstrated that 3,3',5-triiodothyronine (T3) induces oxidative stress in rat liver, with enhancement in the DNA binding of nuclear factor-kappaB (NF-kappaB) and the NF-kappaB-dependent expression of tumor ...

Administration of single doses of 0.1 mg of L-3,3′,5-triiodothyronine (T3)/kg for 3 consecutive days to fed rats elicited a marked increase both in the opsonized zymosan-induced luminol-amplified integrated chemiluminescence ...