Browsing by Author "García de Gracia, Francisco"

Now showing items 1-2 of 2

    • DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced ... 
      Fröhlich, Alvaro; Rojas Araya, Bárbara; Pereira Montecinos, Camila; Dellarossa, Alessandra; Toro Ascuy, Daniela; Prades Pérez, Yara; García de Gracia, Francisco; Garcés Alday, Andrea; Rubilar, Paulina S.; Valiente Echeverría, Fernando; Ohlmann, Théophile; Soto Rifo, Ricardo (2016)
      DEAD-box RNA helicase DDX3 is a host factor essential for HIV-1 replication and thus, a potential target for novel therapies aimed to overcome viral resistance. Previous studies have shown that DDX3 promotes nuclear ...
    • Epitranscriptomic regulation of HIV-1 full-length RNA packaging 
      Pereira Montecinos, Camila; Toro Ascuy, Daniela; Ananías Sáez, Catarina; Gaete Argel, Aracelly; Rojas Fuentes, Cecilia; Riquelme Barrios, Sebastián; Rojas Araya, Bárbara; García de Gracia, Francisco; Aguilera Cortés, Paulina; Chnaiderman Figueroa, Jonas; Acevedo Acevedo, Mónica; Valiente Echeverría, Fernando; Soto Rifo, Ricardo (Oxford University Press, 2022)
      During retroviral replication, the full-length RNA serves both as mRNA and genomic RNA. However, the mechanisms by which the HIV-1 Gag protein selects the two RNA molecules that will be packaged into nascent virions remain ...