Browsing by Author "González Candia, Alejandro"

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Artículo

Cardioprotective antioxidant and anti-inflammatory mechanisms induced by intermittent hypobaric hypoxia

González Candia, Alejandro; Candia Henríquez, Alejandro Andrés; Paz, Adolfo; Mobarec Lubies, Fuad Cristóbal Rachid; Urbina Varela, Rodrigo; Campo, Andrea del; Herrera Videla, Emilio Augusto; Castillo Peñaloza, Rodrigo Luis (MDPI, 2022)

More than 80 million people live and work (in a chronic or intermittent form) above 2500 masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 100,000 people work in high-altitude ...
Artículo

Cinaciguat (BAY-582667) modifies cardiopulmonary and systemic circulation in chronically hypoxic and pulmonary ...

Beñaldo Fuentes, Felipe Augusto; Araya Quijada, Claudio Enrique; Ebensperger Darrouy, Germán; Herrera Videla, Emilio Augusto; Reyes, Roberto V.; Moraga, Fernando A.; Riquelme Herrera, Alexander Nathan; González Candia, Alejandro; Castillo Galán, Sebastián; Valenzuela, Guillermo J.; Serón Ferré, María Josefa; Llanos, Aníbal J. (Frontiers Media, 2022)

Neonatal pulmonary hypertension (NPHT) is produced by sustained pulmonary vasoconstriction and increased vascular remodeling. Soluble guanylyl cyclase (sGC) participates in signaling pathways that induce vascular vasodilation ...
Artículo

Editorial: Mechanisms of ischemia-reperfusion injury in animal models and clinical conditions: current ...

Castillo Peñaloza, Rodrigo Luis; González Candia, Alejandro; Carrasco, Rodrigo (Frontiers Media, 2022)
Artículo

Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep

Torres, Flavio; González Candia, Alejandro; Montt, Camilo; Ebensperger Darrouy, Germán; Chubretovic, Magdalena; Serón Ferré, María; Reyes Catalán, Víctor; Llanos Mansilla, Jorge; Herrera Videla, Emilio (Wiley, 2015)

Pulmonary hypertension of the newborn (PHN) constitutes a critical condition with severe cardiovascular and neurological consequences. One of its main causes is hypoxia during gestation, and thus, it is a public health ...
Artículo

Omega3 Supplementation and Intermittent Hypobaric Hypoxia Induce Cardioprotection Enhancing Antioxidant ...

Herrera Videla, Emilio; Farías, Jorge; González Candia, Alejandro; Short, Stefania; Carrasco Pozo, Catalina; Castillo Peñaloza, Rodrigo (MDPI, 2015)

Intermittent hypobaric hypoxia (IH) is linked with oxidative stress, impairing cardiac function. However, early IH also activate cardio-protective mechanisms. Omega 3 fatty acids (Ω3) induce cardioprotection by reducing ...
Artículo

Ω3 supplementation and intermittent hypobaric hypoxia induce cardioprotection enhancing antioxidant mechanisms ...

Herrera, Emilio A.; Farías, Jorge G.; González Candia, Alejandro; Short, Stefania E.; Carrasco Pozo, Catalina; Castillo, Rodrigo L. (MDPI, 2015)

Intermittent hypobaric hypoxia (IH) is linked with oxidative stress, impairing cardiac function. However, early IH also activate cardio-protective mechanisms. Omega 3 fatty acids (Ω3) induce cardioprotection by reducing ...