Browsing by Author "Gutiérrez, Matias"

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    • Mild hypothermia upregulates myc and xbp1s expression and improves anti TNF alpha production in CHO cells 
      Torres, Mauro; Zúniga, Roberto; Gutiérrez, Matias; Vergara, Mauricio; Collazo, Norberto; Reyes, Juan; Berrios, Julio; Aguillón Gutiérrez, Juan Carlos; Molina Sampayo, María Carmen; Altamirano, Claudia (Public Library Science, 2018)
      Chinese hamster ovary (CHO) cells are the most frequently used host for commercial production of therapeutic proteins. However, their low protein productivity in culture is the main hurdle to overcome. Mild hypothermia has ...