Browsing by Author "Guzmán Martínez, Leonardo"

Now showing items 1-5 of 5

    • CDK5: A Unique CDK and Its Multiple Roles in the Nervous System 
      Cortés, Nicole; Guzmán Martínez, Leonardo; Andrade, Víctor; González, Andrea; Maccioni Baraona, Ricardo (IOS Press, 2019)
      The cyclin-dependent kinase 5 (CDK5) is known as an exceptional component of the CDK family, due to its characteristic regulatory pathways and its atypical roles in comparison to the classical cyclins. Despite its functional ...
    • Emerging Noninvasive Biomarkers for Early Detection of Alzheimer's Disease 
      Guzmán Martínez, Leonardo; Farías, Gonzalo A.; Maccioni Baraona, Ricardo (2012)
      Alzheimer's disease (AD) diagnosis still depends on the triad of clinical, imaging and neuropsychological testing. The development of accurate, easy to use and inexpensive biological markers for AD is a long-standing ...
    • Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel ... 
      Morales, Inelia; Guzmán Martínez, Leonardo; Cerda Troncoso, Cristóbal; Farías, Gonzalo A.; Maccioni Baraona, Ricardo (Frontiers Research Foundation, 2014)
      Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old. The molecular and cellular alterations that trigger this disease are still diffuse, one of the reasons for the delay in finding an ...
    • Pathway to Tau Modifications and the Origins of Alzheimer's Disease 
      Maccioni Baraona, Ricardo; Tapia, José Pablo; Guzmán Martínez, Leonardo (Elsevier Inc., 2018)
    • The Alz-tau Biomarker for Alzheimer's Disease: Study in a Caucasian Population 
      Guzmán Martínez, Leonardo; Tapia, José Pablo; Farías, Gonzalo A.; González, Andrea; Estrella, Matías; Maccioni Baraona, Ricardo (IOS Press, 2019)
      The establishment of a molecular biomarker for early detection of Alzheimer's disease (AD) is critical for diagnosis and follow up of patients, and as a quantitative parameter in the evaluation of potential new drugs to ...