Browsing by Author "Hattersley, Andrew T."

Now showing items 1-2 of 2

    • Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3 
      Rubio Cabezas, Oscar; Jensen, Jan N.; Hodgson, María Isabel; Codner Dujovne, Ethel; Ellard, Sian; Serup, Palle; Hattersley, Andrew T. (2011-04)
      OBJECTIVE—NEUROG3 plays a central role in the development of both pancreatic islets and enteroendocrine cells. Homozygous hypomorphic missense mutations in NEUROG3 have been recently associated with a rare form of ...
    • Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations 
      Pearson, Ewan R.; Flechtner, Isabelle; Njølstad, Pal R.; Malecki, Maciej T.; Flanagan, Sarah E.; Larkin, Brian; Ashcroft, Frances M.; Klimes, Iwar; Codner Dujovne, Ethel; Lotova, Violeta; Slingerland, Annabelle S.; Shield, Julian; Robert, Jean-Jacques; Holst, Jens J.; Clark, Penny M.; Ellard, Sian; Søvik, Oddmund; Polak, Michel; Hattersley, Andrew T. (MASSACHUSETTS MEDICAL SOC, 2006-08-03)
      BACKGROUND: Heterozygous activating mutations in KCNJ11, encoding the Kir6.2 subunit of the ATP-sensitive potassium (K(sub ATP)) channel, cause 30 to 58 percent of cases of diabetes diagnosed in patients under six months ...