Browsing by Author "Hermoso, Marcela Alejandra"

Now showing items 1-9 of 9

    • Butyrate and the fine-tuning of colonic homeostasis: implication for inflammatory bowel diseases 
      Gasaly Retamal, Naschla Yazmín Ivana; Hermoso, Marcela Alejandra; Gotteland, Martín (MDPI, 2020)
      This review describes current evidence supporting butyrate impact in the homeostatic regulation of the digestive ecosystem in health and inflammatory bowel diseases (IBDs). Butyrate is mainly produced by bacteria from ...
    • Caracterización estructural, funcional y farmacológica de un anticuerpo monoclonal humano contra la proteína ... 
      Novoa Gundel, Pedro Francisco (Universidad de Chile, 2023)
      La colitis ulcerosa (CU) es uno de los principales tipos de enfermedades inflamatorias intestinales (EII), que tiene una incidencia creciente en Chile durante los últimos años, y una etiología multifactorial que involucra: ...
    • Crosstalk between tumor-infiltrating immune cells and cancer-associated Fibroblasts in tumor growth and ... 
      Soongsathitanon, Jarupa; Jamjuntra, Pranisa; Sumransub, Nuttavut; Yangngam, Supaporn; Fuente, Marjorie de la; Landskron Ramos, Glauben Tamara; Thuwajit, Peti; Hermoso, Marcela Alejandra; Thuwajit, Chanitra (Hindawi, 2021)
      Signals from the tumor microenvironment (TME) have a profound influence on the maintenance and progression of cancers. Chronic inflammation and the infiltration of immune cells in breast cancer (BC) have been strongly ...
    • Dysregulated immune responses in COVID-19 patients correlating with disease severity and invasive oxygen ... 
      García González, Paulina; Tempio Sepúlveda, Fabián Ignacio; Fuentes, Camila; Merino, Consuelo; Vargas, Leonardo; Simon, Valeska; Ramírez Pereira, Mirliana; Rojas, Verónica; Tobar Almonacid, Eduardo Andres; Landskron Ramos, Glauben Tamara; Araya, Juan Pablo; Navarrete, Mariela; Bastías Oñate, Carla Belén; Tordecilla Fernández, Rocío Pilar; Varas, Macarena A.; Maturana, Pablo; Marcoleta Caldera, Andrés Esteban; Allende Connelly, Miguel Luis; Naves Pichuante, Rodrigo Antonio; Hermoso, Marcela Alejandra; Salazar Onfray, Flavio Andrés; López Nitsche, Mercedes Natalia; Bono Merino, María Rosa; Osorio Olivares, Fabiola Beatriz (Frontiers Media, 2021)
      The prognosis of severe COVID-19 patients has motivated research communities to uncover mechanisms of SARS-CoV-2 pathogenesis also on a regional level. In this work, we aimed to understand the immunological dynamics of ...
    • Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment 
      Hanus, Michelle; Parada Venegas, Daniela; Landskron Ramos, Glauben Tamara; Wielandt, Ana María; Hurtado, Claudia; Álvarez, Karin; Hermoso, Marcela Alejandra; López Köstner, Francisco; Fuente, Marjorie de la (Frontiers Media, 2021)
      Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other cancers, CRC is a multifactorial disease due to the combined effect of genetic and environmental factors. Most cases are sporadic, but a ...
    • Landscapes and bacterial signatures of mucosa-associated intestinal microbiota in Chilean and Spanish ... 
      Chamorro, Nayaret; Montero, David A.; Gallardo Schall, Pablo Alfredo; Farfán Urzúa, Mauricio; Contreras, Mauricio; Fuente, Marjorie, de la; Dubois Camacho, Karen; Hermoso, Marcela Alejandra; Quera, Rodrigo; Pizarro Guajardo, Marjorie; Paredes Sabja, Daniel; Ginard, Daniel; Rossello Mora, Ramón; Vidal Álvarez, Roberto (Shared Science, 2021)
      Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn's disease (CD), cause chronic inflammation of the gut, affecting millions of people worldwide. IBDs have been frequently associated with ...
    • Regulation of the intestinal extra-adrenal steroidogenic pathway component LRH-1 by glucocorticoids in ... 
      Landskron Ramos, Glauben Tamara; Dubois Camacho, Karen; Orellana Serradell, Octavio Andrés; Fuente López, Majorie de la; Parada Venegas, Daniela Estefani; Bitrán Ambler, Mirit Luisa; Díaz Jiménez, David; Tang, Shuang; Cidlowski, John A.; Li, Xiaoling; Molina, Héctor; González, Carlos M.; Simian, Daniela; Lubascher, Jaime; Pola, Víctor; Montecino, Martín; Blokzijl, Tjasso; Faber, Klaas Nico; González Burgos, María Julieta; Quera, Rodrigo; Hermoso, Marcela Alejandra (MDPI, 2022)
      Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) and can be treated with glucocorticoids (GC), although some patients are unresponsive to this therapy. The transcription factor LRH-1/NR5A2 is critical to ...
    • Small RNA expression profiling reveals hsa-miR-181d-5p downregulation associated with TNF-α overexpression ... 
      Castro Masso, Isabel Verónica; Carvajal Garcés, Patricia Alejandra; Jara, Daniela; Aguilera, Sergio; Heathcote Pérez, Benjamín Norman; Barrera, María José; Aliaga Tobar, Víctor Manuel; Maracaja Coutinho, Vinicius; Urzúa Tobar, Ulises; Quest, Andrew Frederick Geoffery; González, Sergio; Claudio, Molina; Hermoso, Marcela Alejandra; González Burgos, María Julieta (Frontiers Media, 2022)
      MicroRNAs (miRNAs) are small non-coding RNAs (sRNA), that alter gene expression by binding to target messenger RNAs (mRNAs) and repressing translation. Dysregulated miRNA expression has been implicated in the pathogenesis ...
    • Type I interferon dependent hsa-miR-145-5p downregulation modulates MUC1 and TLR4 overexpression in salivary ... 
      Jara, Daniela; Carvajal, Patricia; Castro Masso, Isabel Verónica; Barrera, María José; Aguilera, Sergio; González, Sergio; Molina, Claudio; Hermoso, Marcela Alejandra; González Burgos, María Antonieta (Frontiers Media, 2021)
      Sjögren’s syndrome (SS) is an autoimmune disease that mainly affects salivary glands (SG) and is characterized by overactivation of the type I interferon (IFN) pathway. Type I IFNs can decrease the levels of hsa-miR-145-5p, ...