Browsing by Author "Herrera Videla, Emilio Augusto"
Now showing items 1-14 of 14
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Biomechanical and structural responses of the aorta to intermittent hypobaric hypoxia in a rat model (Nature, 2022)High altitude hypoxia is a condition experienced by diverse populations worldwide. In addition, several jobs require working shifts where workers are exposed to repetitive cycles of hypobaric hypoxia and normobaric ...
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(Nature, 2021)The present study involves experiments and modelling aimed at characterizing the passive structural mechanical behavior of the chronic hypoxic lamb thoracic aorta, whose gestation, birth and postnatal period were carried ...
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(MDPI, 2022)More than 80 million people live and work (in a chronic or intermittent form) above 2500 masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 100,000 people work in high-altitude ...
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(Frontiers Media, 2022)Neonatal pulmonary hypertension (NPHT) is produced by sustained pulmonary vasoconstriction and increased vascular remodeling. Soluble guanylyl cyclase (sGC) participates in signaling pathways that induce vascular vasodilation ...
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(Universidad de Chile, 2021)La Hipertensión Arterial Pulmonar Neonatal (HAPN) es un síndrome cardiopulmonar grave, caracterizado por un aumento patológico de la presión arterial pulmonar media (mPAP>20 mmHg), que comúnmente cursa con taquipnea e ...
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(Universidad de Chile, 2023)Introducción. La HAP (hipertensión pulmonar) es una enfermedad infrecuente, progresiva y potencialmente letal que compromete vidas de pacientes jóvenes, principalmente mujeres en plena etapa de productividad personal, ...
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(Universidad de Chile, 2024)Antecedentes. La gestación en hipoxia hipobárica por altura geográfica altera la función vascular en humanos y animales no adaptados a tierras altas. Estructuralmente, puede existir una remodelación, caracterizada por ...
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(Frontiers Media, 2021)Fetal chronic hypoxia leads to intrauterine growth restriction (IUGR), which is likely to reduce oxygen delivery to the brain and induce long-term neurological impairments. These indicate a modulatory role for oxygen in ...
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(Frontiers Media, 2021)An estimated human population of 170 million inhabit at high-altitude (HA, above 2,500 m). The potential pathological effects of HA hypobaric hypoxia during gestation have been the focus of several researchers around the ...
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(Universidad de Chile, 2022)Adecuados niveles de oxígeno y nutrientes son fundamentales para el correcto desarrollo de la gestación. Alteraciones en estos factores, como, por ejemplo, una disminución del oxígeno ambiental y/o una malnutrición materna ...
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(Wiley, 2021)Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and molecular levels, this study investigated whether maternal treatment with melatonin protects against programmed ...
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(MDPI, 2021)Pulmonary arterial hypertension of newborns (PAHN) constitutes a critical condition involving both severe cardiac remodeling and right ventricle dysfunction. One main cause of this condition is perinatal hypoxia and oxidative ...
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(Springernature, 2021)BACKGROUND: In the fetus, the appropriate balance of prooxidants and antioxidants is essential to negate the detrimental effects of oxidative stress on lung maturation. Antioxidants improve respiratory function in postnatal ...
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(Frontiers Media, 2022)Calcium signaling is key for the contraction, differentiation, and proliferation of pulmonary arterial smooth muscle cells. Furthermore, calcium influx through store-operated channels (SOCs) is particularly important in ...
