Browsing by Author "Hidalgo, Yessia"

Now showing items 1-6 of 6

    • Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance 
      Ruiz, Paulina; Maldonado, Paula; Hidalgo, Yessia; Sauma Mahaluf, Daniela; Rosemblatt Silber, Mario César; Bono Merino, María Rosa (Frontiers Media, 2015)
      The induction of donor-specific transplant tolerance is one of the main goals of modern immunology. Establishment of a mixed chimerism state in the transplant recipient has proven to be a suitable strategy for the induction ...
    • Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection 
      Moore, Carolina; Tejón, Gabriela; Fuentes, Camila; Hidalgo, Yessia; Bono Merino, María Rosa; Maldonado, Paula; Fernández, Ricardo; Wood, Kathryn; Fierro, Juan; Rosemblatt Silber, Mario César; Sauma Mahaluf, Daniela; Bushell, Andrew (Wiley-Blackwell, 2015)
      CD4+CD25+Foxp3+ regulatory T (Treg) cells mediate immunological self-tolerance and suppress immune responses. Retinoic acid (RA), a natural metabolite of vitamin A, has been reported to enhance the differentiation of ...
    • T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 ... 
      Nuñez, Sarah; Saez, Juan José; Fernández, Dominique; Flores Santibañez, Felipe; Álvarez, Karla; Tejón, Gabriela; Ruiz, Paulina; Maldonado, Paula; Hidalgo, Yessia; Manriquez, Valeria; Bono Merino, María Rosa; Rosemblatt Silber, Mario César; Sauma Mahaluf, Daniela (Blackwell Publishing, 2013)
      T helper type 17 (Th17) lymphocytes are found in high frequency in tumour-burdened animals and cancer patients. These lymphocytes, characterized by the production of interleukin-17 and other pro-inflammatory cytokines, ...
    • The multifaceted roles of B cells in the thymus: from immune tolerance to autoimmunity 
      Castañeda, Justine; Hidalgo, Yessia; Sauma Mahaluf, Daniela Macarena; Rosemblatt Silber, Mario Cesar; Bono Merino, María Rosa; Núñez, Sarah (Frontiers Media, 2021)
      The thymus is home to a significant number of resident B cells which possess several unique characteristics regarding their origin, phenotype and function. Evidence shows that they originate both from precursors that ...
    • Transplant Tolerance: New Insights and Strategies for Long-Term Allograft Acceptance 
      Ruiz, Paulina; Maldonado, Paula; Hidalgo, Yessia; Gleisner, Alejandra; Sauma Mahaluf, Daniela; Silva, Cinthia; Saez, Juan José; Nuñez, Sarah; Rosemblatt Silber, Mario César; Bono Merino, María Rosa (Hindawi, 2013)
      One of the greatest advances in medicine during the past century is the introduction of organ transplantation. This therapeutic strategy designed to treat organ failure and organ dysfunction allows to prolong the survival ...
    • Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation 
      Tejón, Gabriela; Manríquez, Valeria; Calisto, Jaime, de; Flores Santibáñez, Felipe; Hidalgo, Yessia; Crisóstomo, Natalia; Fernández, Dominique; Sauma Mahaluf, Daniela; Mora, J.; Bono Merino, María Rosa; Rosemblatt Silber, Mario César (Hindawi Publishing, 2015)
      Maintaining the identity of Foxp3+ regulatory T cells (Tregs) is critical for controlling immune responses in the gut, where an imbalance between Tregs and T effector cells has been linked to inflammatory bowel disease. ...