Browsing by Author "Huidobro Toro, Juan Pablo"

Now showing items 1-4 of 4

    • 4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A ... 
      Villalobos, Claudio A.; Bull, Paulina; Sáez, Patricio; Cassels Niven, Bruce; Huidobro Toro, Juan Pablo (Nature Publishing Group, 2004-02-04)
      1 We recently described that several 2-(2,5-dimethoxy-4-substituted phenyl)ethylamines (PEAs), including 4-I¼2C-I, 4-Br¼2C-B, and 4-CH3¼2C-D analogs, are partial agonists at 5-HT2C receptors, and show low or even negligible ...
    • ATP released by electrical stimuli elicits calcium transients and gene expression in skeletal muscle 
      Buvinic, Sonja; Almarza, Gonzalo; Bustamante, Mario; Casas, Mariana; López, Javiera; Riquelme, Manuel; Sáez, Juan Carlos; Huidobro Toro, Juan Pablo; Jaimovich Pérez, Enrique (2009)
      ATP released from cells is known to activate plasma membrane P2X (ionotropic) or P2Y (metabotropic) receptors. In skeletal muscle cells, depolarizing stimuli induce both a fast calcium signal associated with contraction ...
    • P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells 
      Barrera Ávalos, Carlos; Briceño, Pedro; Valdés, Daniel; Imarai, Mónica; Leiva Salcedo, Elías; Rojo, Leonel E.; Milla, Luis A.; Huidobro Toro, Juan Pablo; Robles Planells, Claudia; Escobar Álvarez, Alejandro; Di Virgilio, Francesco; Morón, Gabriel; Sauma Mahaluf, Daniela Macarena; Acuña Castillo, Claudio (Cell, 2021)
      T cell activation requires the processing and presentation of antigenic peptides in the context of a major histocompatibility complex (MHC complex). Cross -dressing is a non-conventional antigen presentation mechanism, ...
    • Stoichiometry and conditional stability constants of Cu(II) or Zn(II) clioquinol complexes; implications ... 
      Ferrada, Evandro; Arancibia, Verónica; Loeb, Bárbara; Norambuena, Ester; Olea Azar, Claudio; Huidobro Toro, Juan Pablo (2007)
      Successful trials with 5-chloro-7-iodo-8-hydroxyquinoline (clioquinol, CQ) for Alzheimer's disease treatment prompted renewed interest in assessing whether its therapeutic action is related to the coordination of neurotoxic ...