Browsing by Author "Jorquera, Gonzalo"

Now showing items 1-6 of 6

    • Activation of the NLRP3 Inflammasome Increases the IL-1 beta Level and Decreases GLUT4 Translocation in ... 
      Americo Da Silva, Luan; Aguilera, Javiera; Quinteros Waltemath, Oscar Alberto; Sánchez Aguilera, Pablo Ignacio; Russell, Javier; Cadagan Fuentes, Cynthia Angelica; Meneses Valdés, Roberto Andrés; Sánchez Vergara, Jeannette Romina; Estrada Hormazábal, Manuel; Jorquera, Gonzalo; Barrientos Briones, Genaro Christian; Llanos Vidal, Paola (MDPI, 2021)
      Low-grade chronic inflammation plays a pivotal role in the pathogenesis of insulin resistance (IR), and skeletal muscle has a central role in this condition. NLRP3 inflammasome activation pathways promote low-grade chronic ...
    • Cav1.1 controls frequency-dependent events regulating adult skeletal muscle plasticity 
      Jorquera, Gonzalo; Altamirano, Francisco; Contreras Ferrat, Ariel Eduardo; Almarza, Gonzalo; Buvinic Radic, Sonja; Jacquemond, Vincent; Jaimovich Pérez, Enrique; Casas Atala, Mariana (The Company of Biologists, 2013)
      An important pending question in neuromuscular biology is how skeletal muscle cells decipher the stimulation pattern coming from motoneurons to define their phenotype as slow or fast twitch muscle fibers. We have previously ...
    • Electrical stimulation induces calcium-dependent up-regulation of neuregulin-1β in dystrophic skeletal ... 
      Juretic Díaz, Nevenka Militza; Jorquera, Gonzalo; Caviedes, Pablo; Jaimovich Pérez, Enrique; Riveros, Nora (2012)
      Duchenne muscular dystrophy (DMD) is a neuromuscular disease originated by reduced or no expression of dystrophin, a cytoskeletal protein that provides structural integrity to muscle fibres. A promising pharmacological ...
    • Membrane depolarization induces calcium-dependent upregulation of Hsp70 and Hmox-1 in skeletal muscle cells 
      Jorquera, Gonzalo; Juretic Díaz, Nevenka Militza; Jaimovich Pérez, Enrique; Riveros, Nora (2009)
      Heat shock proteins (HSPs) are a conserved family of cytoprotective polypeptides, synthesized by cells in response to stress. Hsp70 and heme oxygenase 1 (Hmox-1) are induced by a variety of cellular stressors in skeletal ...
    • NLRP3 inflammasome: potential role in obesity related low-grade inflammation and insulin resistance in ... 
      Jorquera, Gonzalo; Russell, Javier; Monsalves Álvarez, Matías; Cruz, Gonzalo; Valladares-Ide, Denisse; Basualto Alarcón, Carla Edith; Barrientos, Genaro; Estrada, Manuel; Llanos, Paola (MDPI, 2021)
      Among multiple mechanisms, low-grade inflammation is critical for the development of insulin resistance as a feature of type 2 diabetes. The nucleotide-binding oligomerization domain-like receptor family (NOD-like) pyrin ...
    • Pannexin-1 and CaV1.1 show reciprocal interaction during excitation–contraction and excitation–transcription ... 
      Jaque Fernández, Francisco Ignacio; Jorquera, Gonzalo; Troc Gajardo, Jennifer; Pietri Rouxel, France; Gentil, Christel; Buvinic Radic, Sonja Milena; Allard, Bruno; Jaimovich Pérez, Enrique Zacarias; Jacquemond, Vincent; Casas Atala, Mariana Victoria (Rockefeller Univ Press, 2021)
      One of the most important functions of skeletal muscle is to respond to nerve stimuli by contracting. This function ensures body movement but also participates in other important physiological roles, like regulation of ...