Browsing by Author "Junqueira, Virginia"
Now showing items 1-13 of 13
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Arisi, Ana Carolina M.; Kiyoko, Simizu; Marisa, Kogake; Barny, Afonso C.D.; Silva, Marcia A.S.; Barros, Silvia B.M.; Boveris, Alberto; Videla Cabrera, Luis; Junqueira, Virginia (1994)Oxidative stress-related parameters in rat brain and liver were evaluated following acute (60 mg/kg i.p., 2 and 24 h after dosing) or short-term (1000 ppm in the diet for 90 days) lindane administration. Both treatments ...
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Videla Cabrera, Luis; Troncoso, P.; Arisi, A. C.M.; Junqueira, Virginia (1997)1. Twenty-four hours after lindane exposure (5-60 mg/kg) a dose-dependent increase in the serum and hepatic levels of the insecticide was observed. Both the basal rate of O2 consumption and the sinusoidal efflux of lactate ...
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Junqueira, Virginia; Simizu, Kiyoko; Videla Cabrera, Luis; Silvia, Silvia B. (1986)The administration of single i.p. doses of lindane (20, 40, 60 and 80 mg/kg) to rats produced a progressive increase in the liver microsomal content of cytochrome P-450 and in the rate of superoxide anion generation, as ...
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Junqueira, Virginia; Simizu, K.; Pimentel, R.; Azzalis, L. A.; Barros, S. B.M.; Koch, O.; Videla Cabrera, Luis (Informa Healthcare, 1991)1. Lindane administered to untreated rats or rats pretreated with phenobarbital (PB) or 3-methylcholanthrene (MC) increased liver lipid peroxidation, of the same magnitude in all groups. 2. PB pretreatment produced a 50% ...
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Fernández Arancibia, Virginia; Simizu, Kiyoko; Barros, Silvia B.M.; Azzalis, Ligia A.; Pimentel, Renato; Junqueira, Virginia; Videla Cabrera, Luis (1991)The effect of hyperthyroidism on liver glutathione (GSH) metabolism was studied in fed rats after the administration of 0.1 mg T3/kg body wt, for 1-3 consecutive days. T3-calorigenesis resulted in elevated rates of ...
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Simon-Giavarotti, Karin A.; Giavarotti, Leandro; Gomes, Ligia F.; Lima, Alessandra F.; Veridiano, Adriano M.; Garcia, Eduardo A.; Mora, Oswaldo A.; Fernández Arancibia, Virginia; Videla Cabrera, Luis; Junqueira, Virginia (2002)The role of Kupffer cells in the hepatocellular injury and oxidative stress induced by lindane (20 mg/kg; 24h) in hyperthyroid rats (daily doses of 0.1 mg L-3,3′,5-triio-dothyronine (T3)/kg for three consecutive days) was ...
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Boveris, Alberto; Llesuy, Susana; Azzalis, Ligia A.; Giavarotti, Leandro; Simon, Karin A.; Junqueira, Virginia; Porta, Eduardo A.; Videla Cabrera, Luis; Lissi Gervaso, Eduardo A. (1997)The influence of acute ethanol administration on the oxidative stress status of rat brain and liver was assessed by in situ spontaneous organ chemiluminescence (CL). Brain and liver CL was significantly increased after ...
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Videla Cabrera, Luis; Smok Sahid, Gladys; Troncoso, Pilar; Simon, Karin A.; Junqueira, Virginia; Fernández Arancibia, Virginia (1995)Parameters related to hepatic oxidative stress, cell injury, phagocytic activity, and liver histology were studied in control rats and in animals subjected to l-3,3′,5-triiodothyronine (T3) and/or lindane administration. ...
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Junqueira, Virginia; Simizu, Kiyoko; Van Halsema, Leonardo; Koch, Osvaldo R.; Barros, Silvia B.M.; Videla Cabrera, Luis (Informa Healthcare, 1988)1. Lindane (60 mg/kg) administered orally to rats increased liver cytochrome P-450 content and superoxide radical (O- 2) generation 24 h after treatment, while formation of thiobarbituric acid reactants and NADPH/ADP-supported ...
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Videla Cabrera, Luis; Simizu, Kiyoko; Barros, Silvia B.M.; Junqueira, Virginia (1989)The effects of lindane administration (25–60 mg kg−1 for 24 h) on hepatic oxygen consumption were studied in the isolated perfused rat liver, in the absence and presence of the iron‐chelator free‐radical scavenger ...
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Videla Cabrera, Luis; Barros, Silvia B.M.; Simizu, Kiyoko; Junqueira, Virginia (1988)The i.p. administration of 60 mg kg−1 body weight of lindane, the γ‐isomer of hexachlorocyclohexane, to fed rats led to an enhancement of hepatic lipid peroxidation after 24 h of treatment. This was evidenced by significant ...
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Junqueira, Virginia; Barros, Silvia B.M.; Simizu, Kiyoko; Fernández Arancibia, Virginia; Carrión, Yasna; Pimentel, Renato; Azzalis, Ligia A.; Videla Cabrera, Luis (1993)The administration of lindane (60 mg/kg) to fed rats diminished the content of hepatic glutathione (GSH) 4 h after treatment, which was recovered at 24 h. At these experimental times, the activities of glutathione peroxidase, ...
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Gomes, L. F.; Gonçalves, L. M.; Fonseca, F. L.A.; Celli, C. M.; Videla Cabrera, Luis; Chaimovich, H.; Junqueira, Virginia (2002)β2-Glycoprotein I (β2GPI) is known to influence macrophage uptake of particles with phosphatidylserine containing surfaces, as apoptotic thymocytes and unilamellar vesicles in vitro. Nevertheless, effects upon macrophage ...