Browsing by Author "Llanos, Aníbal J."

Now showing items 1-3 of 3

    • Antenatal melatonin modulates an enhanced antioxidant/pro-oxidant ratio in pulmonary hypertensive newborn sheep 
      Gonzalez-Candia, Alejandro; Veliz, Marcelino; Carrasco-Pozo, Catalina; Castillo, Rodrigo L.; Cárdenas, J. Cesar; Ebensperger, Germán; Reyes, Roberto V.; Llanos, Aníbal J.; Herrera, Emilio A. (Elsevier B.V., 2019)
      Chronic hypobaric hypoxia during fetal and neonatal life induces neonatal pulmonary hypertension. Hypoxia and oxidative stress are driving this condition, which implies an increase generation of reactive oxygen species ...
    • Cinaciguat (BAY-582667) modifies cardiopulmonary and systemic circulation in chronically hypoxic and pulmonary ... 
      Beñaldo Fuentes, Felipe Augusto; Araya Quijada, Claudio Enrique; Ebensperger Darrouy, Germán; Herrera Videla, Emilio Augusto; Reyes, Roberto V.; Moraga, Fernando A.; Riquelme Herrera, Alexander Nathan; González Candia, Alejandro; Castillo Galán, Sebastián; Valenzuela, Guillermo J.; Serón Ferré, María Josefa; Llanos, Aníbal J. (Frontiers Media, 2022)
      Neonatal pulmonary hypertension (NPHT) is produced by sustained pulmonary vasoconstriction and increased vascular remodeling. Soluble guanylyl cyclase (sGC) participates in signaling pathways that induce vascular vasodilation ...
    • Melatonin reduces oxidative stress in the right ventricle of newborn sheep gestated under chronic hypoxia 
      González Candia, Alejandro Antonio; Arias, Pamela V.; Aguilar, Simón A.; Figueroa, Esteban G.; Reyes, Roberto V.; Ebensperger Darrouy, Germán; Llanos, Aníbal J.; Herrera Videla, Emilio Augusto (MDPI, 2021)
      Pulmonary arterial hypertension of newborns (PAHN) constitutes a critical condition involving both severe cardiac remodeling and right ventricle dysfunction. One main cause of this condition is perinatal hypoxia and oxidative ...