Browsing by Author "Llanos Silva, Miguel"
Now showing items 1-17 of 17
-
Ronco Macchiavello, Ana María; Llanos Silva, Miguel; Tamayo, Daniela; Hirsch Birn, Sandra (2007)Background and aims: Several studies have shown the beneficial effects of folate treatment in improving cardiovascular function. However, the mechanisms involved have not been clearly identified. The aim of this study is ...
-
Valenzuela, Carina; Castillo, Valeska; Ronco Macchiavello, Ana María; Aguirre, Carolina; Hirsch Birn, Sandra; Llanos Silva, Miguel (Sociedad Medica de Santiago, 2014)The endocannabinoid system (SEC) is an important modulator of several metabolic functions. This system is composed by cannabinoid receptors type 1 and 2 (RCB1 and RCB2), their endogenous ligands, known as endocannabinoids, ...
-
Ronco Macchiavello, Ana María; Llanos Silva, Miguel; Tamayo, Daniela; Hirsch Birn, Sandra (2007)The endogenous cannabinoid receptor agonist anandamide (AEA) exerts vascular effects such as vasodilatation and hypotension. In this study, we determined the effect of AEA on endothelin-1 production by cultured human ...
-
Moraga,; Llanos Silva, Miguel; Ronco Macchiavello, Ana María (BioScientifica Ltd., 1997)In this work, the involvement of arachidonic acid (AA) in the luteinizing hormone and human chorionic gonadotrophin (LH/hCG) action on Leydig cells was studied. Experiments were first designed to evaluate [14C]AA incorporation ...
-
Ronco Macchiavello, Ana María; Moraga,; Llanos Silva, Miguel (2002)We have previously demonstrated that the release of arachidonic acid (AA) from human chorionic gonadotropin (hCG)-stimulated Leydig cells occurs in a dose- and time-dependent manner. In addition, the amount of AA released ...
-
Zepeda Iriarte, Ramiro; Castillo, Paula; Sáez, Daniel; Llanos Silva, Miguel; Ronco Macchiavello, Ana María (Springer, 2012)It has been suggested that prenatal exposure to cadmium may alter the cardiovascular function during adulthood. Using the left coronary artery ligation model of acute myocardial infarction, we studied the cardiac ...
-
Harari, Florencia; Ronco Macchiavello, Ana María; Concha, Gabriela; Llanos Silva, Miguel; Grandér, Margaretha; Castro, Francisca; Palm, Brita; Nermell, Barbro; Vahter, Marie (2012)The transfer of lithium and boron from exposed mothers to fetuses and breast-fed infants was investigated in areas in northern Argentina and Chile with up to 700 μg. lithium/L and 5-10. mg. boron/L in drinking water. ...
-
Castaño, Erika; Caviedes, Lorena; Hirsch Birn, Sandra; Llanos Silva, Miguel; Iñíguez Vila, Germán; Ronco Macchiavello, Ana María (Public Library of Science, 2017)Folate deficiency during pregnancy has been related to low birth weight, preterm (PT) birth and other health risks in the offspring; however, it is unknown whether prematurity is related to low folate transport through ...
-
Peñailillo, Reyna; Guajardo, Angélica; Llanos Silva, Miguel; Hirsch Birn, Sandra; Ronco Macchiavello, Ana María (Public Library of Science, 2015)In the placenta, 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) limits fetal glucocorticoid exposure and its inhibition has been associated to low birth weight. Its expression, encoded by the HSD11B2 gene is regulated ...
-
Hirsch Birn, Sandra; Ronco Macchiavello, Ana María; Pinardi Testa, Gianni; Montequin, María José; Leiva Balich, Laura; Maza Cave, María Pía de la; Llanos Silva, Miguel; Bunout Barnett, Daniel (CHURCHILL LIVINGSTONE, 2008-12)Background: Endothelial dysfunction is a key process in atherosclerosis. Hypomethylation is one of the postulated mechanisms involved in atherogenesis and is mainly secondary to a decrease in essential factors such as, ...
-
Castro, Francisca; Harari, Florencia; Llanos Silva, Miguel; Vahter, Marie; Ronco Macchiavello, Ana María (Thieme Medical Publishers, Inc., 2014)Copyright © 2014 by Thieme Medical Publishers, Inc. Objective To determine the daily intake of essential micronutrients and toxic elements through breast milk in exclusive and nonexclusive breastfed infants living in an ...
-
Hirsch Birn, Sandra; Ronco Macchiavello, Ana María; Guerrero Bosagna, Carlos; Maza Cave, María Pía de la; Leiva Balich, Laura; Barrera Acevedo, María; Llanos Silva, Miguel; Alliende Rodríguez, María Angélica; Silva, Francisca; Bunout Barnett, Daniel (ELSEVIER, 2008-12)Objective: We assessed the impact of high serum folate concentration oil erythrocyte S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH) concentrations, SAM/SAH ratio, CpG methylation levels across the promoter region ...
-
Valenzuela, Carina; Aguirre, Carolina; Castillo, Valeska; Ronco Macchiavello, Ana María; Llanos Silva, Miguel (2010)Endocannabinoids are the endogenous ligands for the cannabinoid receptors type 1 and 2. These membrane receptors are responsible for the psychotropic effects of Cannabis Sativa, when bound to its active component known ...
-
Caviedes, Lorena; Iñíguez Vila, Germán; Hidalgo, Paulina; Castro, Juan José; Castaño, Erika; Llanos Silva, Miguel; Hirsch Birn, Sandra; Ronco Macchiavello, Ana María (W.B. Saunders Ltd, 2016)© 2015 Elsevier Ltd. All rights reserved.Background Adequate folate levels are essential for successful pregnancy outcomes. We aimed to study the relationship between placental mRNA and protein levels of folate transporters ...
-
Llanos Silva, Miguel; Torres Morales, Patricio; Riffo, Marta S. (1993)Phospholipase A2 and lysophospholipids have been implicated in the mammalian sperm acrosome reaction. In this study we further investigated the role of this enzyme and lysophospholipids on the acrosome reaction of hamster ...
-
Torres Morales, Patricio; Llanos Silva, Miguel; Gutierrez, Gabriela; Kohen Skop, Paulina; Vigil, Pilar; Vantman, David (Oxford University Press, 1992)In this study, we have evaluated the relationship between the acrosome reaction-inducing activity of individual human follicular fluid samples and their steroid content. Eighteen samples of follicular fluid were obtained ...
-
Valenzuela, Carina A.; Castillo, Valeska A.; Aguirre, Carolina A.; Ronco Macchiavello, Ana María; Llanos Silva, Miguel (2011)Perinatal stress may cause metabolic and hormonal disruptions during adulthood. The aim of this study was to evaluate the effects of early postnatal nociceptive stimulation (NS) on body weight and other metabolic ...