Browsing by Author "Mancilla, Héctor"

Now showing items 1-3 of 3

    • EGF and its receptor ( EGF-R ) in in vitro implanted mouse blastocysts 
      Mancilla, Héctor; Faûndez,; Gonzalez, (1996)
      In vitro mouse blastocysts produce a serum dependent outgrowth of trophoblast considered similar to in utero implantation. We observed in this system that EGF induces morphological and biochemical modifications on implanted ...
    • Glutathione Depletion Induces Spermatogonial Cell Autophagy 
      Mancilla, Héctor; Maldonado, Rodrigo; Cereceda, Karina; Villarroel Espíndola, Franz; Montes de Oca, Marco; Angulo, Constanza; Castro, Maite A.; Slebe, Juan C.; Vera, Juan C.; Lavandero González, Sergio (Wiley-Blackwell, 2015)
      The development and survival of male germ cells depend on the antioxidant capacity of the seminiferous tubule. Glutathione (GSH) plays an important role in the antioxidant defenses of the spermatogenic epithelium. Autophagy ...
    • Potent neutralization of clinical isolates of SARS‑CoV‑2 D614 and G614 variants by a monomeric, sub‑nanomolar ... 
      Valenzuela Nieto, Guillermo; Jara, Ronald; Watterson, Daniel; Modhiran, Naphak; Amarilla, Alberto A.; Himelreichs, Johanna; Khromykh, Alexander A.; Salinas Rebolledo, Constanza; Pinto, Teresa; Cheuquemilla, Yorka; Margolles, Yago; López González del Rey, Natalia; Miranda Chacón, Zaray; Cuevas, Alexei; Berking, Anne; Deride, Camila; González Moraga, Sebastián; Mancilla, Héctor; Maturana, Daniel; Langer, Andreas; Toledo, Juan Pablo; Müller, Ananda; Uberti, Benjamín; Krall, Paola; Ehrenfeld, Pamela; Blesa, Javier; Chana Cuevas, Pedro; Rehren, Germán; Schwefel, David; Fernández, Luis Ángel; Rojas Fernández, Alejandro (Nature, 2021)
      Despite unprecedented global efforts to rapidly develop SARS-CoV-2 treatments, in order to reduce the burden placed on health systems, the situation remains critical. Effective diagnosis, treatment, and prophylactic ...