Browsing by Author "Mancilla, Jerson"

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Artículo

Comparison of alloxan and streptozotocin induced diabetes in rats: Differential effects on microsomal drug ...

Vega, Patricio; Gaule, Carlos; Mancilla, Jerson; Del Villar, Eugenia (1993)

1. Liver microsomes from alloxan or streptozotocin diabetic rats displayed differential drug metabolizing abilities in vitro. 2. Only streptozotocin liver microsomes exhibited changes in the cytochrome P-450 normal spectral ...
Artículo

Increased activity of testosterone hydroxylases in liver microsomes of diabetic rats treated with insulin

Villar, Eugenia del; Mancilla, Jerson; Vega, Patricio; Sánchez, Emilio (1985)

1. 1. Liver microsomes from alloxan diabetic rats displayed decreased activity to hydroxylate testosterone only at the 2-α and 6-β positions. 2. 2. Diabetic insulin-treated rats showed higher hydroxylase activities than ...
Artículo

Inhibition of tumoral cell respiration and growth by nordihydroguaiaretic acid

Pavani, M.; Fones, Elizabeth; Oksenberg Reisberg, Danny; García, Manuel; Hernández, Carolina; Cordano, Gianni; Muñoz, Sergio; Mancilla, Jerson; Guerrero, Aanibal; Ferreira Parker, Jorge (PERGAMON-ELSEVIER SCIENCE LTD, 1994-11-16)

The effects of nordihydroguaiaretic acid (NDGA), best known as an inhibitor of lipoxygenase activities, on the culture growth, oxygen consumption, ATP level, viability, and redox state of some electron carriers of intact ...