Browsing by Author "Martínez Olguín, Matías"

Now showing items 1-9 of 9

    • Detección de problemas relacionados a medicamentos en pacientes adultos atendidos en un servicio de urgencia ... 
      Chávez Pineda, Camila (Universidad de Chile, 2016)
      Antecedentes: Los servicios de urgencias (SU) reúnen una serie de características que los convierten en uno de los servicios más complejos, poseen factores propios de la urgencia médica, que sumado a una población actual ...
    • Determinación de problemas relacionados a medicamentos al ingreso en pacientes adultos en un servicio de urgencia 
      Muñoz González, Ana Luisa (Universidad de Chile, 2017)
      El uso de medicamentos conlleva riesgos, ya sea por eventos adversos como por falta de cumplimiento. Los problemas relacionados a medicamentos (PRM) pueden presentarse con diversa gravedad y tener como consecuencia la ...
    • Pharmacodynamic polymorphisms 
      Martínez Olguín, Matías; Cerpa Castro, Leslie; Morales Varela, Nelson; Quiñones Sepúlveda, Luis (Springer, 2021)
    • Pharmacogenomics: basis and milestones 
      Cerpa Castro, Leslie; Varela Figueroa, Nelson; Martínez Olguín, Matías; Quiñones Sepúlveda, Luis (Springer, 2021)
      The genomic interindividual heterogeneity for proper pharmacotherapy remains a significant challenge for research, clinical decision-making, and the design of clinical trials. Translation of the obtained genomic information ...
    • Pharmacogenomics: challenges and future perspectives 
      Quiñones Sepúlveda, Luis; Martínez Olguín, Matías; Cerpa Castro, Leslie; Varela Figueroa, Nelson (Springer, 2021)
      Pharmacogenetics is the science of understanding how genetic variability influences drug treatment outcomes and generally refers to the effects of a single genetic marker on pharmacokinetics and pharmacodynamics of ...
    • Pharmacogenomics: genetic polymorphisms 
      Varela Figueroa, Nelson; Cerpa Castro, Leslie; Martínez Olguín, Matías; Quiñones Sepúlveda, Luis (Springer, 2021)
      It has been estimated that the human genome harbors about 30,000 protein-coding genes. Within these proteins we find transporters, metabolizing enzymes, and therapeutic drug targets. The analysis of human genomic ...
    • Pharmacokinetic polymorphisms 
      Martínez Olguín, Matías; Cerpa Castro, Leslie; Varela Figueroa, Nelson; Quiñones Sepúlveda, Luis (Springer, 2021)
      A polymorphism is a genetic variant that leads to at least two non-rare phenotypes with a frequency of 1% or greater in a population. When the variant is in a gene that codifies proteins involved in drug absorption, ...
    • Relationship Between Pharmacokinetics and Pharmacogenomics and Its Impact on Drug Choice and Dose Regimens (2018) 
      Martínez Olguín, Matías; Quiñones Sepúlveda, Luis (Springer, 2018)
      Definition Pharmacokinetics can be defined as the relationship between the administered dose and the plasma concentration of a drug, which implies the study of the different processes of absorption, distribution, metabolism, ...
    • Relationship between pharmacokinetics and pharmacogenomics, and its impact on drug choice and dose regimens (2024) 
      Martínez Olguín, Matías; Quiñones Sepúlveda, Luis (Springer, 2024)
      Pharmacokinetics can be defined as the relationship between the administered dose and plasma concentration of a drug, which implies the study of different processes, such as absorption, distribution, biotransformation, ...