Browsing by Author "Mella, Jaime"

Now showing items 1-2 of 2

    • Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs 
      Suárez Rozas, Cristian; Simpson, Sebastián; Fuentes Retamal, Sebastián; Catalán, Mabel; Ferreira, Jorge; Theoduloz, Cristina; Mella, Jaime; Cabezas, David; Cassels Niven, Bruce; Yáñez, Claudia; Castro Castillo, Vicente (Elsevier Ltd, 2019)
      © 2018 1,4-Naphthoquinone derivatives have been widely documented with regard to their biological properties, and particularly their anticancer activities. In the 9,10-anthraquinone family, aza-annulation involving one of ...
    • Structure-activity relationships based on 3D-QSAR CoMFA/CoMSIA and design of aryloxypropanol-amine agonists ... 
      Lorca, Marcos; Morales Verdejo, César; Vásquez Velásquez, David; Andrades Lagos, Juan Andrés; Campanini Salinas, Javier; Soto Delgado, Jorge; Recabarren Gajardo, Gonzalo; Mella, Jaime (MDPI, 2018)
      The wide tissue distribution of the adrenergic 3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there ...