Now showing items 1-5 of 5

    • Campo, Andrea del; Salamanca, Catalina; Fajardo, Ángelo; Díaz Castro, Francisco; Bustos, Catalina; Calfío, Camila; Troncoso Cotal, Rodrigo Hernán; Pastene Navarrete, Edgar Rafael; Acuña Castillo, Claudio; Milla, Luis A.; Villarroel, Carlos A.; Cubillos, Francisco A.; Aranda, Mario; Rojo, Leonel E. (MDPI, 2021)
      Type 2 diabetes and obesity are major problems worldwide and dietary polyphenols have shown efficacy to ameliorate signs of these diseases. Anthocyanins from berries display potent antioxidants and protect against weight ...
    • Bergeron, Sadie A.; Milla, Luis A.; Villegas, Rosario; Shen, Meng-Chieh; Burgess, Shawn M.; Allende Connelly, Miguel; Karlstrom, Rolf O.; Palma Alvarado, Verónica (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2007-12-11)
      The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. ...
    • Barrera Ávalos, Carlos Esteban; Díaz, Ximena; Madrid, Sebastián; Michelson, Sofía A.; Robles Planells, Claudia Julieta; Sánchez Guerrero, Giselle; Ahumada, Viviana; Mella Torres, Andrea Jesús; Rojo, Leonel E.; Imarai Bahamonde, Mónica; Milla, Luis A.; Leiva Salcedo, Elías; Murgas, Paola; Fernández, Ricardo; Escobar, Alejandro; Acuña Castillo, Claudio (Hindawi, 2021)
      Active immunotherapy against cancer is based on immune system stimulation, triggering efficient and long-lasting antigen-specific immune responses. Immunization strategies using whole dead cells from tumor tissue, containing ...
    • Barrera Ávalos, Carlos; Briceño, Pedro; Valdés, Daniel; Imarai, Mónica; Leiva Salcedo, Elías; Rojo, Leonel E.; Milla, Luis A.; Huidobro Toro, Juan Pablo; Robles Planells, Claudia; Escobar Álvarez, Alejandro; Di Virgilio, Francesco; Morón, Gabriel; Sauma Mahaluf, Daniela Macarena; Acuña Castillo, Claudio (Cell, 2021)
      T cell activation requires the processing and presentation of antigenic peptides in the context of a major histocompatibility complex (MHC complex). Cross -dressing is a non-conventional antigen presentation mechanism, ...
    • Milla, Luis A.; Cortés, Claudio R.; Hödar Quiroga, Christian; Oñate, Maritza G.; Cambiazo Ayala, Liliana; Burgess, Shawn M.; Palma Alvarado, Verónica (BIOMED CENTRAL LTD, 2012-01-03)
      Background: The increasing number of developmental events and molecular mechanisms associated with the Hedgehog (Hh) pathway from Drosophila to vertebrates, suggest that gene regulation is crucial for diverse cellular ...