Browsing by Author "Miranda, Mariana R."

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    • Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about ... 
      Seguel, Verónica; Castro, Lorena; Reigada, Chantal; Cortés, Leonel; Díaz, María V.; Miranda, Mariana R.; Pereira, Claudio A.; Lapier, Michel; Campos Estrada, Carolina; Morello Casté, Antonio; Kemmerling Weis, Ulrike; Maya, Juan D.; Lopez Muñoz, Rodrigo (Elsevier, 2016)
      Benznidazole is the first-line drug used in treating Chagas disease, which is caused by the parasite Trypanosoma cruzi (T. cruzi). However, benznidazole has limited efficacy and several adverse reactions. Pentamidine is ...
    • Pentamidine exerts in vitro and in vivo anti Trypanosoma cruzi activityand inhibits the polyamine transport ... 
      Díaz, María V.; Miranda, Mariana R.; Campos Estrada, Carolina; Reigada, Chantal; Maya Arango, Juan; Pereira, Claudio A.; López Muñoz, Rodrigo (Elsevier, 2014)
      Pentamidine is an antiprotozoal and fungicide drug used in the treatment of leishmaniasis and Africantrypanosomiasis. Despite its extensive use as antiparasitic drug, little evidence exists about the effect ofpentamidine ...