Now showing items 1-14 of 14

    • Sagüez May, Juan Francisco (Universidad de Chile, 2017)
      La presente investigación tiene por objetivo analizar las relaciones de pareja, y en ese sentido el amor, en el contexto de la sociedad contemporánea. Para esto, se ponen en tensión dos conceptos: el erotismo, desde la ...
    • Durán Aniotz, Claudia; Morales, Rodrigo; Moreno González, Inés; Hu, Ping Ping; Soto, Claudio (BioMed Central, 2013)
      Background: One of the main features of Alzheimer’s disease (AD) is the presence of Aβ deposits, which accumulate in the brain years before the onset of symptoms. We and others have demonstrated that cerebral Aβ-amyloidosis ...
    • Castilla, Joaquín; Morales, Rodrigo; Saá, Paula; Barría, Marcelo; Gambetti, Pierluigi; Soto, Claudio (NATURE PUBLISHING GROUP, 2008-10-08)
      Prions are the infectious agents responsible for prion diseases, which appear to be composed exclusively by the misfolded prion protein (PrPSc). Disease is transmitted by the autocatalytic propagation of PrPSc misfolding ...
    • Castilla, Joaquín; González Romero, Dennisse; Saá, Paula; Morales, Rodrigo; Castro, Jorge de; Soto, Claudio (CELL PRESS, 2008-09-05)
      Prions are unconventional infectious agents composed exclusively of misfolded prion protein (PrPSc), which transmits the disease by propagating its abnormal conformation to the cellular prion protein (PrPC). A key ...
    • Barría, Marcelo; Mukherjee, Abhisek; González Romero, Dennisse; Morales, Rodrigo; Soto, Claudio (2009)
      Prions are the proteinaceous infectious agents responsible for Transmissible Spongiform Encephalopathies. Compelling evidence supports the hypothesis that prions are composed exclusively of a misfolded version of the prion ...
    • Pizarro Aránguiz, Nicolás; García Mendoza, Diego; Muñoz Obregón, Rubén; San Martín Núñez, Betty; Morales, Rodrigo (Pontificia Universidad Catolica de Chile, Facultad de Agronomia e Ingenieria Forestal, 2018)
      According to a One Health perspective, the importance of persistent organic pollutants (POPs) must be assessed because of their impact on the environment, food chain and human health. However, information on these toxic ...
    • Muñoz, Camila; Villalobos, Rodrigo; Peralta, Alejandra María Teresa; Morales, Rodrigo; Urrutia, Natalie Louise; Ungerfeld, Emilio Mauricio (MDPI, 2021)
      Research is ongoing to find nutritional methane (CH4 ) mitigation strategies with persistent effects that can be applied to grazing ruminants. Lipid addition to dairy cow diets has shown potential as means to decrease ...
    • Morales, Rodrigo; Estrada, Lisbell D.; Diaz-Espinoza, Rodrigo; Morales-Scheihing, Diego; Jara, Maria C.; Castilla, Joaquin; Soto, Claudio (2010)
      The central event in protein misfolding disorders (PMDs) is the accumulation of a misfolded form of a naturally expressed protein. Despite the diversity of clinical symptoms associated with different PMDs, many similarities ...
    • Morales, Rodrigo; Estrada, Lisbell D.; Díaz Espinoza, Rodrigo; Morales Scheihing, Diego; Jara, María C.; Castilla, Joaquín; Soto, Claudio (2010-03-31)
      The central event in protein misfolding disorders (PMDs) is the accumulation of a misfolded form of a naturally expressed protein. Despite the diversity of clinical symptoms associated with different PMDs, many similarities ...
    • Castillo Sepúlveda, Laura (Universidad de Chile, 2013-12)
      La presente investigación busca conocer las narrativas maternidad/paternidad, familia y crianza en padres y madres adoptivos/as y se enmarcaría en la nueva línea de estudios que tienen como objetivo enfocarse en las ...
    • Morales, Rodrigo; Abid, Karim; Soto, Claudio (ELSEVIER SCIENCE BV, 2007-06)
      Prions are unconventional infectious agents responsible for transmissible spongiform encephalopathies. Compelling evidences indicate that prions are composed exclusively by a misfolded form of the prion protein (PrPSc) ...
    • Morales, Rodrigo; Buytaert-Hoefen, Kimberley A.; González Romero, Dennisse; Castilla, Joaquín; Hansen, Eric T.; Hlavinka, Dennis; Goodrich, Raymond P.; Soto, Claudio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008-12-12)
      The link between a new variant form of Creutzfeldt-Jakob disease (vCJD) and the consumption of prion contaminated cattle meat as well as recent findings showing that vCJD can be transmitted by blood transfusion have raised ...
    • García González, Paulina; Morales, Rodrigo; Hoyos, Lorena; Maggi, Jaxaira; Campos, Javier; Pesce Reyes, Bárbara; Gárate, David; Larrondo Lillo, Milton; González González, Rodrigo; Soto Sáez, Lilian; Ramos, Verónica; Tobar, Pía; Molina, María Carmen; Pino Lagos, Karina; Catalán Martina, Diego; Aguillón Gutiérrez, Juan Carlos (BioMed Central, 2013)
      Background: Generation of tolerogenic dendritic cells (TolDCs) for therapy is challenging due to its implications for the design of protocols suitable for clinical applications, which means not only using safe products, ...
    • Park, Kyung Won; Eun Kim, Gyoung; Morales, Rodrigo; Moda, Fabio; Moreno González, Inés; Concha Marambio, Luis; Lee, Amy S.; Hetz Flores, Claudio; Soto, Claudio (Nature Publishing Group, 2017)
      © The Author(s) 2017. Prion diseases are fatal neurodegenerative disorders affecting several mammalian species, characterized by the accumulation of the misfolded form of the prion protein, which is followed by the induction ...