Browsing by Author "Muñoz, Juan P."

Now showing items 1-9 of 9

    • Characterization of high-risk HPV/EBV co-presence in pre-malignant cervical lesions and squamous cell carcinomas 
      Blanco Santana, Rancés; Carrillo Beltrán, Diego Antonio; Muñoz, Juan P.; Osorio, Julio C.; Tapia Pineda, Julio César; Burzi, Verónica A.; Gallegos Méndez, Iván Marcelo; Calaf, Gloria M.; Chabay, Paola; Aguayo González, Francisco Renán (MDPI, 2022)
      High-risk human papillomaviruses (HR-HPVs) are the etiological agents of cervical cancer. However, a low proportion of HR-HPV-infected women finally develop this cancer, which suggests the involvement of additional cofactors. ...
    • Epstein–Barr virus infection in lung cancer: insights and perspectives 
      Osorio, Julio C.; Blanco Santana, Rancés; Corvalán, Alejandro H.; Muñoz, Juan P.; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2022)
      Lung cancer (LC) is the leading cause of cancer death worldwide. Tobacco smoke is the most frequent risk factor etiologically associated with LC, although exposures to other environmental factors such as arsenic, radon or ...
    • Gene signatures induced by ionizing radiation as prognostic tools in an in vitro experimental breast cancer model 
      Calaf, Gloria M.; Crispin, Leodan A.; Roy, Debasish; Aguayo González, Francisco; Muñoz, Juan P.; Bleak, Tammy C. (MDPI, 2021)
      Simple Summary The present work analyzed the expression of genes involved in radiation, using an in vitro experimental breast cancer model developed by the combined treatment of low doses of high linear energy transfer ...
    • Human papillomavirus in breast carcinogenesis: a passenger, a cofactor, or a causal agent? 
      Blanco, Rances; Carrillo Beltrán, Diego Antonio; Muñoz, Juan P.; Corvalán, Alejandro H.; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary Breast cancer (BC) is the most frequent tumor in women worldwide. A minority of BC patients have a family history of the disease, suggesting the importance of environmental and lifestyle factors. Human ...
    • Human papillomavirus infection in oral squamous cell carcinomas from Chilean patients 
      Reyes Rojas, Montserrat; Rojas Alcayaga, Gonzalo; Pennacchiotti Vidal, Gina; Carrillo, Diego; Muñoz, Juan P.; Peña, Nelson; Montes, Rodrigo; Lobos Jaimes-Freyre, Nelson; Aguayo, Francisco (Elsevier, 2015)
      Human papillomavirus (HPV) is the causal agent of cervical, anogenital and a subset of oropharyngeal carcinomas. In addition, the role of HPV in oral carcinogenesis has been suggested, although the findings are inconclusive. ...
    • Muscarinic receptors associated with cancer 
      Calaf, Gloria M.; Crispin, Leodan A.; Muñoz, Juan P.; Aguayo González, Francisco Renán; Bleak, Tammy C. (MDPI, 2022)
      Simple Summary Recently, cancer research has described the presence of the cholinergic machinery, specifically muscarinic receptors, in a wide variety of cancers due to their activation and signaling pathways associated ...
    • Role of pirin, an oxidative stress sensor protein, in epithelial carcinogenesis 
      Pérez Domínguez, Francisco Javier; Carrillo Beltrán, Diego Antonio; Blanco Santana, Rancés; Muñoz, Juan P.; León Cruz, Grettell; Corvalán, Alejandro H.; Urzúa Tobar, Ulises de la Cruz; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary Pirin is a protein which is detected at low levels in normal tissues. However, it is detected at high levels in multiple cancers, particularly in melanomas, cervical cancer or squamous cell lung carcinomas. ...
    • Tobacco smoke activates human papillomavirus 16 p97 promoter and cooperates with high-risk E6/E7 for oxidative ... 
      Peña, Nelson; Carrillo, Diego; Muñoz, Juan P.; Chnaiderman, Jonás; Urzúa, Ulises; León, Oscar; Tornesello, Maria L.; Corvalán, Alejandro H.; Soto Rifo, Ricardo; Aguayo, Francisco (Public Library of Science, 2015)
      We have previously shown a functional interaction between human papillomavirus type 16 (HPV-16) E6 and E7 oncoproteins and cigarette smoke condensate (CSC) in lung cells suggesting cooperation during carcinogenesis. The ...
    • Tubulin, actin, and tau protein interactions and the study of their macromolecular assemblies 
      Farías, Gustavo A.; Muñoz, Juan P.; Garrido, Jorge; Maccioni Baraona, Ricardo (2002)
      The intracellular polymerization of cytoskeletal proteins into their supramolecular assemblies raises many questions regarding the regulatory patterns that control this process. Binding experiments using the ELISA solid ...