Browsing by Author "Muñoz, Nicolás"

Now showing items 1-9 of 9

    • ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation 
      Henríquez, Mauricio; Herrera Molina, Rodrigo; Valdivia, Alejandra; Alvarez, Alvaro; Kong, Milene; Muñoz, Nicolás; Eisner, Verónica; Jaimovich Pérez, Enrique; Schneider, Pascal; Quest, Andrew F. G.; Leyton Campos, Lisette (2011)
      Thy-1, an abundant mammalian glycoprotein, interacts with avβ3 integrin and syndecan-4 in astrocytes and thus triggers signaling events that involve RhoA and its effector p160ROCK, thereby increasing astrocyte adhesion to ...
    • Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models 
      Lobos González, Lorena; Aguilar Guzmán, Lorena Andrea; Fernández Ruiz, Jaime Gonzalo; Muñoz, Nicolás; Hossain, Mehnaz; Bieneck, Simone; Silva, Verónica; Burzioc, Verónica; Sviderskayae, Elena V.; Bennett, Dorothy C.; Leyton Campos, Lisette; Quest, Andrew F. G. (Lippincott Williams & Wilkins, 2014)
      Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been ...
    • Caveolin-1-mediated suppression of cyclooxygenase-2 via a β-catenin-Tcf/Lef-dependent transcriptional ... 
      Rodríguez, Diego A.; Tapia, Julio; Fernández, Jaime G.; Torres Gómez, Vicente; Muñoz, Nicolás; Galleguillos, Daniela; Leyton Campos, Lisette; Quest, Andrew F. G. (2009)
      Augmented expression of cyclooxygenase-2 (COX-2) and enhanced production of prostaglandin E2 (PGE2) are associated with increased tumor cell survival and malignancy. Caveolin-1 is a scaffold protein that has been proposed ...
    • Direct Thy-1/alpha(V)beta(3) integrin interaction mediates neuron to astrocyte communication 
      Hermosilla, Tamara; Muñoz, Daniel; Herrera Molina, Rodrigo; Valdivia, Alejandra; Muñoz, Nicolás; Nham, Sang-Uk; Schneider, Pascal; Burridge, Keith; Quest, Andrew F. G.; Leyton Campos, Lisette (ELSEVIER, 2008-06)
      Thy-1 is an abundant neuronal glycoprotein of poorly defined function. We recently provided evidence indicating that Thy-1 clusters a beta(3)-containing integrin in astrocytes to induce tyrosine phosphorylation, RhoA ...
    • Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alpha v ... 
      Ávalos, Ana María; Valdivia, A. D.; Muñoz, Nicolás; Herrera Molina, Rodrigo; Tapia Pineda, Julio; Lavandero González, Sergio; Chiong Lay, Mario; Burridge, Keith; Schneider, P.; Quest, Andrew F. G.; Leyton Campos, Lisette (COMPANY OF BIOLOGISTS LTD, 2009-10)
      Clustering of alpha v beta 3 integrin after interaction with the RGD-like integrin-binding sequence present in neuronal Thy-1 triggers formation of focal adhesions and stress fibers in astrocytes via RhoA activation. A ...
    • Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with αvβ3 ... 
      Avalos, Ana María; Valdivia, Alejandra D.; Muñoz, Nicolás; Herrera Molina, Rodrigo; Tapia, Julio C.; Lavandero González, Sergio; Chiong Lay, Mario; Burridge, Keith; Schneider, Pascal; Quest, Andrew F. G.; Leyton Campos, Lisette (2009)
      Clustering of αvβ3 integrin after interaction with the RGD-like integrin-binding sequence present in neuronal Thy-1 triggers formation of focal adhesions and stress fibers in astrocytes via RhoA activation. A putative ...
    • Reflexionando lo político-ambiental. Dossier compilatorio del Ciclo de Coloquios de Estudios Político-Ambientales. 
      Cuevas Gutiérrez, Camila; Martínez, Francisco; Schnake, Felipe; Abad, Paulo; Muñoz, Nicolás; Cariaga, Valentina; Alarcón, Taira (Universidad de Chile, 2024)
      El presente documento es una iniciativa de estudiantes de postgrado de la Universidad de Chile, provenientes de la Facultad de Gobierno, la Facultad de Ciencias Sociales (FACSO) y la Facultad de Ciencias Físicas y Matemáticas ...
    • Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4 
      Kong, Milene; Muñoz, Nicolás; Valdivia, Alejandra; Alvarez, Alvaro; Herrera Molina, Rodrigo; Cárdenas, Areli; Schneider, Pascal; Burridge, Keith; Quest, Andrew F. G.; Leyton Campos, Lisette (2013)
      Cell adhesion to the extracellular matrix proteins occurs through interactions with integrins that bind to Arg-Gly-Asp (RGD) tripeptides, and syndecan-4, which recognizes the heparin-binding domain of other proteins. Both ...
    • Thy-1-mediated cell–cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4 
      Kong, Milene; Muñoz, Nicolás; Valdivia, Alejandra; Álvarez, Ávaro; Herrera Molina, Rodrigo; Cárdenas, Areli; Schneider, Pascal; Burridge, Keith; Quest, Andrew F. G.; Leyton Campos, Lisette (Elsevier, 2013)
      Cell adhesion to the extracellular matrix proteins occurs through interactions with integrins that bind to Arg-Gly-Asp (RGD) tripeptides, and syndecan-4, which recognizes the heparin-binding domain of other proteins. ...