Browsing by Author "Niu, Youguo"

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Artículo

Impaired Nitric Oxide Mediated Vasodilation In The Peripheral Circulation In The R6/2 Mouse Model Of ...

Kane, Andrew D.; Niu, Youguo; Herrera Videla, Emilio; Morton, A. Jennifer; Giussani, Dino A. (Nature, 2016)

Recent evidence shows that the Huntington's disease (HD) extends beyond the nervous system to other sites, including the cardiovascular system. Further, the cardiovascular pathology pre-dates neurological decline, however ...
Artículo

Melatonin modulates the fetal cardiovascular defense response to acute hypoxia

Thakor, Avnesh S.; Allison, Beth J.; Niu, Youguo; Botting, Kimberley J.; Serón Ferré, María; Herrera Videla, Emilio; Giussani, Dino A. (Wiley & Sons, 2015)

Experimental studies in animal models supporting protective effects on the fetus of melatonin in adverse pregnancy have prompted clinical trials in human pregnancy complicated by fetal growth restriction. However, the ...
Artículo

Molecular regulation of lung maturation in near-term fetal sheep by maternal daily vitamin C treatment in ...

McGillick, Erin; Orgeig, Sandra; Allison, Beth J.; Brain, Kirsty L.; Niu, Youguo; Itani, Nozomi; Skeffington, Katie; Kane, Andrew; Herrera Videla, Emilio Augusto; Morrison, Janna L.; Giussani, Dino A. (Springernature, 2021)

BACKGROUND: In the fetus, the appropriate balance of prooxidants and antioxidants is essential to negate the detrimental effects of oxidative stress on lung maturation. Antioxidants improve respiratory function in postnatal ...
Artículo

Reduced Cystathionine g-Lyase and Increased miR-21 Expression Are Associated with Increased Vascular ...

Cindrova Davies, Tereza; Herrera Videla, Emilio; Niu, Youguo; Kingdom, John; Giussani, Dino A.; Burton, Graham J. (Elsevier, 2013)

Increased vascular impedance in the fetoplacental circulation is associated with fetal hypoxia and growth restriction. We sought to investigate the role of hydrogen sulfide (H2S) in regulating vasomotor tone in ...