Browsing by Author "Olmedo, Ivonne"

Now showing items 1-5 of 5

    • EPAC expression and function in cardiac fibroblasts and myofibroblasts 
      Olmedo, Ivonne; Muñoz, Claudia; Guzmán, Nancy; Catalán, Mabel; Vivar, Raúl; Ayala, Pedro; Humeres Martínez, Claudio; Aránguiz, Pablo; García Nannig, Lorena; Velarde, Victoria; Díaz Araya, Guillermo (Elsevier, 2013)
      In the heart, cardiac fibroblasts (CF) and cardiac myofibroblasts (CMF) are the main cells responsible for wound healing after cardiac insult. Exchange protein activated by cAMP (EPAC) is a downstream effector of cAMP, ...
    • Gold Nanoparticles and Microwave Irradiation Inhibit Beta-Amyloid Amyloidogenesis 
      Araya, Eyleen; Olmedo, Ivonne; Bastus, Neus G.; Guerrero, Simón; Puntes, Víctor F.; Giralt, Ernest; Kogan Bocian, Marcelo (SPRINGER, 2008-11)
      Peptide-Gold nanoparticles selectively attached to beta-amyloid protein (A beta) amyloidogenic aggregates were irradiated with microwave. This treatment produces dramatic effects on the A beta aggregates, inhibiting both ...
    • How Changes in the Sequence of the Peptide CLPFFD-NH2 Can Modify the Conjugation and Stability of Gold ... 
      Olmedo, Ivonne; Araya, Eyleen; Sanz, Fausto; Medina, Elias; Arbiol, Jordi; Toledo, Pedro; Álvarez Lueje, Alejandro; Giralt, Ernest; Kogan Bocian, Marcelo (American Chemical Society, 2008-05-30)
      In a previous work, we studied the interaction of -amyloid fibrils (A ) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the ...
    • Participación de Miro1 en hipertrofia en cardiomiocitos de rata neonata 
      Conejeros Vásquez, Carolina (Universidad de Chile, 2017)
      La hipertrofia cardiaca es una respuesta adaptativa del corazón frente a situaciones de sobrecarga de trabajo, la cual funciona inicialmente como un mecanismo compensatorio. Sin embargo, la hipertrofia sostenida en el ...
    • Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability 
      Copaja, Miguel; Venegas, Daniel; Aranguiz, Pablo; Canales, Jimena; Vivar, Raúl; Avalos, Yennifer; García Nannig, Lorena; Chiong Lay, Mario; Olmedo, Ivonne; Catalán, Mabel; Leyton Campos, Lisette; Lavandero González, Sergio; Díaz Araya, Guillermo (Elsevier, 2012)
      Statins reduce the isoprenoids farnesyl and geranylgeranyl pyrophosphate, essential intermediates, which control a diversity of cellular events such as cytoskeleton integrity, adhesion, migration and viability. Cardiac ...