Browsing by Author "Orellana Serradell, Octavio Andrés"

Now showing items 1-3 of 3

    • Regulation of the intestinal extra-adrenal steroidogenic pathway component LRH-1 by glucocorticoids in ... 
      Landskron Ramos, Glauben Tamara; Dubois Camacho, Karen; Orellana Serradell, Octavio Andrés; Fuente López, Majorie de la; Parada Venegas, Daniela Estefani; Bitrán Ambler, Mirit Luisa; Díaz Jiménez, David; Tang, Shuang; Cidlowski, John A.; Li, Xiaoling; Molina, Héctor; González, Carlos M.; Simian, Daniela; Lubascher, Jaime; Pola, Víctor; Montecino, Martín; Blokzijl, Tjasso; Faber, Klaas Nico; González Burgos, María Julieta; Quera, Rodrigo; Hermoso, Marcela Alejandra (MDPI, 2022)
      Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) and can be treated with glucocorticoids (GC), although some patients are unresponsive to this therapy. The transcription factor LRH-1/NR5A2 is critical to ...
    • The cytoplasmic region of SARAF reduces triple-negative breast cancer metastasis through the regulation of ... 
      Saldías Maulén, María Paz; Cruz Núñez, Pablo; Silva Del Canto, Ian; Orellana Serradell, Octavio Andrés; Lavanderos Andrade, Boris Joan; Maureira Fuentes, Diego Javier; Pinto Sierralta, Raquel Cristina; Cerda Arancibia, Oscar Alejandro (MDPI, 2023)
      Triple-negative breast cancer has a poor prognosis and is non-responsive to first-line therapies; hence, new therapeutic strategies are needed. Enhanced store-operated Ca2+ entry (SOCE) has been widely described as a ...
    • TRP channels interactome as a novel therapeutic target in breast cancer 
      Saldías Maulén, María Paz; Maureira Fuentes, Diego Javier; Orellana Serradell, Octavio Andrés; Silva del Canto, Ian; Lavanderos Andrade, Boris Joan; Cruz, Pablo; Torres Paredes, Camila Esperanza; Cáceres Lluch, Mónica; Cerda Arancibia, Oscar Alejandro (MDPI, 2021)
      Breast cancer is one of the most frequent cancer types worldwide and the first cause of cancer-related deaths in women. Although significant therapeutic advances have been achieved with drugs such as tamoxifen and trastuzumab, ...