Browsing by Author "Ortiz, Rina"

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Artículo

Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic ...

Wehinger, Sergio; Ortiz, Rina; Díaz, María Inés; Aguirre, Adam; Valenzuela, Manuel; Llanos Vidal, Paola; Mc Master, Christopher; Leyton Campos, Lisette; Quest, Andrew F. G. (Elsevier, 2015)

A considerable body of evidence exists implicating high levels of free saturated fatty acids in beta pancreatic cell death, although the molecular mechanisms and the signaling pathways involved have not been clearly ...
Artículo

Rab5 is required in metastatic cancer cells for caveolin-1-enhanced Rac1 activation, migration and invasion

Díaz, Jorge; Mendoza, Pablo; Ortiz, Rina; Díaz, Natalia; Leyton Campos, Lisette; Stupack, Dwayne; Quest, Andrew F. G.; Torres, Vicente A. (Company of Biologists Ltd, 2014)

Rab5 is a small GTPase that regulates early endosome trafficking and other cellular processes, including cell adhesion and migration. Specifically, Rab5 promotes Rac1 activation and cancer cell migration, but little is ...