Browsing by Author "Paris, Irmgard"

Now showing items 1-3 of 3

    • Dopamine and L-Dopa as selective endogenous neurotoxins 
      Segura Aguilar, Juan Ernesto; Ahumada Castro, Ulises; Paris, Irmgard (2023)
      Selective neurotoxins have the ability to exert their neurotoxic effects in dopaminergic neurons. This could depend on their affinity to the dopamine transporter. The possible molecular mechanisms involved in dopamine and ...
    • Mechanisms of Dopamine Oxidation and Parkinson’s Disease 
      Segura Aguilar, Juan Ernesto; Paris, Irmgard (Springer, 2023)
      Dopamine’s ability to oxidize to aminochrome explains why this molecule may be a neurotoxic compound that induces toxicity in both cell lines and animal models. Spontaneous dopamine oxidation is prevented by vesicular ...
    • One-electron reduction of 6-hydroxydopamine quinone is essential in 6-hydroxydopamine neurotoxicity 
      Villa, Monica; Muñoz, Patricia; Ahumada-Castro, Ulises; Paris, Irmgard; Jiménez, Ana; Martínez, Isabel; Sevilla, Francisca; Segura Aguilar, Juan (2013)
      6-Hydroxydamine has widely been used as neurotoxin in preclinical studies related on the neurodegenerative process of dopaminergic neurons in Parkinson's disease based on its ability to be neurotoxic as a consequence of ...