Browsing by Author "Pereira, Claudio A."

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    • Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about ... 
      Seguel, Verónica; Castro, Lorena; Reigada, Chantal; Cortés, Leonel; Díaz, María V.; Miranda, Mariana R.; Pereira, Claudio A.; Lapier, Michel; Campos Estrada, Carolina; Morello Casté, Antonio; Kemmerling Weis, Ulrike; Maya, Juan D.; Lopez Muñoz, Rodrigo (Elsevier, 2016)
      Benznidazole is the first-line drug used in treating Chagas disease, which is caused by the parasite Trypanosoma cruzi (T. cruzi). However, benznidazole has limited efficacy and several adverse reactions. Pentamidine is ...