Browsing by Author "Pihán, Philippe"

Now showing items 1-2 of 2

    • A phenolic-rich extract from ugni molinae berries reduces abnormal protein aggregation in a cellular model ... 
      Pérez Arancibia, Rodrigo Nicolás; Ordóñez, José Luis; Rivas, Alexis; Pihán, Philippe; Sagredo, Alfredo; Ahumada, Ulises; Barriga, Andrés; Seguel, Ivette; Cárdenas, César; Vidal, René L.; Hetz Flores, Claudio Andres; Delporte Vergara, Carla Luz (Public Library Science, 2021)
      Accumulation of misfolded proteins in the brain is a common hallmark of most age-related neurodegenerative diseases. Previous studies from our group identified the presence of anti-inflammatory and antioxidant compounds ...
    • Role of the unfolded protein response in organ physiology: lessons from mouse models 
      Cornejo, Víctor Hugo; Pihán, Philippe; Vidal, René Luis; Hetz Flores, Claudio (2013)
      The endoplasmic reticulum (ER) is a key subcellular compartment involved in the folding and maturation of around one-third of the total proteome. Accumulation of misfolded proteins in the ER lumen engages a signal transduction ...