Browsing by Author "Pino Lagos, Karina"
Now showing items 1-15 of 15
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Carrasco, Tania Gajardo; Morales, Rodrigo A.; Pérez, Francisco; Terraza, Claudia; Yáñez, Luz; Campos Mora, Mauricio; Pino Lagos, Karina (Frontiers Media S.A., 2015)© 2015 Gajardo Carrasco, Morales, Pérez, Terraza, Yáñez, Campos-Mora and Pino-Lagos. IL-33 is a known member of the IL-1 cytokine superfamily classically named "atypical" due to its diverse functions. The receptor for this ...
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Gajardo Carrasco, Tania; Morales, Rodrigo A.; Pérez Bravo, Francisco; Terraza, Claudia; Yáñez, Luz; Campos Mora, Mauricio; Pino Lagos, Karina (Frontiers Research Foundation, 2015)IL-33 is a known member of the IL-1 cytokine superfamily classically named “atypical” due to its diverse functions. The receptor for this cytokine is the ST2 chain (or IL-1RL1), part of the IL-1R family, and the accessory ...
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Rojas Pérez, Carolina Isabel; Gálvez Jirón, Felipe; Solminihac, Javiera de; Padilla, Cristina; Cárcamo, Ignacio; Villalón, Natalia; Kurte, Mónica; Pino Lagos, Karina (Hindawi, 2022)The microbiome corresponds to the genetic component of microorganisms (archaea, bacteria, phages, viruses, fungi, and protozoa) that coexist with an individual. During the last two decades, research on this topic has become ...
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Pino Lagos, Karina; Michea, Paula; Sauma Mahaluf, Daniela; Alba, Andrea; Morales, Jorge; Bono Merino, María Rosa; Fierro, Alberto; Rosemblatt Silber, Mario César (Society of Biology of Chile, 2010)One of the mechanisms for generation of tolerance involves immature dendritic cells (DCs) and a subpopulation of regulatory CD4+ CD25+ T lymphocytes (TREG). The purpose of this work was to analyze how Cyclosporine A (CsA), ...
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Catalán Martina, Diego; Pino Lagos, Karina (Frontiers Media, 2016)
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Rojas Pérez, Carolina Isabel (Universidad de Chile, 2023)La hidrólisis del AMP extracelular gatillada por la ecto-5'-nucleotidasa CD73 genera adenosina (ADO), una potente molécula inmunosupresora que limita la inflamación. Los linfocitos T (LTs) reguladores murinos inducidos ...
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Terraza Aguirre, Claudia Fernanda (Universisdad de Chile, 2016)Interleuquina-33, citoquina miembro de la familia de IL-1, posee un efecto modulador en distintas poblaciones celulares del sistema inmune, que incluyen respuestas que van desde la inflamación hasta la tolerancia inmune. ...
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Campos Mora, Mauricio Alejandro (Universidad de Chile, 2014)Durante el rechazo a trasplantes alogénicos, varios tipos de células inmunes, incluyendo células dendríticas, células T CD4+ y CD8+, entre otras, recirculan entre el injerto y el ganglio linfático drenante más cercano, ...
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Gajardo Carrasco, Tania Fernanda (Universisdad de Chile, 2015)Recientemente, Ia citoquina miembro de la familia de la lL-1, IL-33, ha sido ampliamente estudiada debido a su variedad de funciones relacionadas a la biología de las células T CD4+. En este trabajo, quisimos evaluar el ...
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Gajardo Carrasco, Tania; Morales, Rodrigo A.; Campos Mora, Mauricio; Campos Acuña, Javier; Pino Lagos, Karina (Wiley-Blackwell, 2015)Interleukin-33 (IL-33) has been a focus of study because of its variety of functions shaping CD4+ T-cell biology. In the present work, we evaluated the modulatory effect of IL-33 on suppressor cells in an in vivo ...
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Gajardo, Tania; Morales, Rodrigo A.; Campos Mora, Mauricio; Campos Acuña, Javier; Pino Lagos, Karina (Blackwell Publishing Ltd, 2015)© 2015 John Wiley & Sons Ltd. Interleukin-33 (IL-33) has been a focus of study because of its variety of functions shaping CD4+ T-cell biology. In the present work, we evaluated the modulatory effect of IL-33 on suppressor ...
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Campos Mora, Mauricio; Morales, Rodrigo A.; Gajardo, Tania; Catalán Martina, Diego; Pino Lagos, Karina (2013)In the immune system, Neuropilin-1 (Nrp1) is a molecule that plays an important role in establishing the immunological synapse between dendritic cells (DCs) and T cells. Recently, Nrp1 has been identified as a marker that ...
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Campos Acuña, Javier; Pérez, Francisco; Narváez, Edgar; Campos Mora, Mauricio; Gajardo, Tania; Catalán Martina, Diego; Aguillón Gutiérrez, Juan Carlos; Pino Lagos, Karina (Future Medicine, 2015)Aim: To date, there is no human dendritic cell (DC) based therapy to prevent allograft rejection in transplanted patients. Here, we evaluate a potential protocol using a murine in vivo transplant model. Materials & ...
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García González, Paulina; Morales, Rodrigo; Hoyos, Lorena; Maggi, Jaxaira; Campos, Javier; Pesce Reyes, Bárbara; Gárate, David; Larrondo Lillo, Milton; González González, Rodrigo; Soto Sáez, Lilian; Ramos, Verónica; Tobar, Pía; Molina, María Carmen; Pino Lagos, Karina; Catalán Martina, Diego; Aguillón Gutiérrez, Juan Carlos (BioMed Central, 2013)Background: Generation of tolerogenic dendritic cells (TolDCs) for therapy is challenging due to its implications for the design of protocols suitable for clinical applications, which means not only using safe products, ...
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Contreras Kallens, Pamina (Universidad de Chile, 2019)La función supresora de las células T reguladoras (Tregs) puede tener efectos negativos sobre la respuesta inmune antitumoral. Por lo tanto, es de gran importancia estudiar los factores que alteran la eficiencia de su ...