Browsing by Author "Posada Duque, Rafael"

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    • CDK5 downregulation enhances synaptic plasticity 
      Posada Duque, Rafael; Ramírez, Omar A.; Härtel, Steffen; Inestrosa, Nibaldo C.; Bodaleo, Felipe; González Billault, Christian; Kirkwood, Alfredo; Cardona Gómez, Gloria (Birkhauser Verlag AG, 2017)
      © 2016, Springer International Publishing. CDK5 is a serine/threonine kinase that is involved in the normal function of the adult brain and plays a role in neurotransmission and synaptic plasticity. However, its over-regulation ...
    • p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing 
      Posada Duque, Rafael; López Tobon, Alejandro; Piedrahita, Diego; González Billault, Christian; Cardona Gómez, Gloria (Wiley & Sons, 2015)
      CDK5 plays an important role in neurotransmission and synaptic plasticity in the normal function of the adult brain, and dysregulation can lead to Tau hyperphosphorylation and cognitive impairment. In a previous study, we ...