Browsing by Author "Rodríguez, Diego A."

Now showing items 1-5 of 5

    • Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis ... 
      Torres Gómez, Vicente; Tapia Pineda, Julio; Rodríguez, Diego A.; Leyton Campos, Lisette; Párraga, Mario; Lisboa, Pamela; Montoya, Margarita; Quest, Andrew F. G. (COMPANY OF BIOLOGISTS LTD, 2006-05-01)
      Caveolin-1 is suggested to act as a tumor suppressor. We tested the hypothesis that caveolin-1 does so by repression of survivin, an Inhibitor of apoptosis protein that regulates cell-cycle progression as well as apoptosis ...
    • Caveolin-1-mediated suppression of cyclooxygenase-2 via a β-catenin-Tcf/Lef-dependent transcriptional ... 
      Rodríguez, Diego A.; Tapia, Julio; Fernández, Jaime G.; Torres Gómez, Vicente; Muñoz, Nicolás; Galleguillos, Daniela; Leyton Campos, Lisette; Quest, Andrew F. G. (2009)
      Augmented expression of cyclooxygenase-2 (COX-2) and enhanced production of prostaglandin E2 (PGE2) are associated with increased tumor cell survival and malignancy. Caveolin-1 is a scaffold protein that has been proposed ...
    • Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1 
      Pihan, Philippe; Lisbona, Fernanda; Borgonovo, Janina Edith; Edwards Jorquera, Sandra Sofía; Nunes Hasler, Paula; Castillo, Karen; Kepp, Oliver; Urra, Hery; Saarnio, Suvi; Vihinen, Helena; Carreras Sureda, Amado; Forveille, Sabrina; Sauvat, Allan; De Giorgis, Daniela; Pupo, Amaury; Rodríguez, Diego A.; Quarato, Giovanni; Sagredo, Alfredo; Lourido Araneda, María Fernanda; Letai, Anthony; Latorre, Ramón; Kroemer, Guido; Demaurex, Nicolás; Jokitalo, Eija; Concha Nordemann, Miguel Luis Angel; Glavic Maurer, Alvaro Alberto; Green, Douglas R.; Hetz Flores, Claudio Andrés (Amer Assoc Advancement Science, 2021)
      Programmed cell death is regulated by the balance between activating and inhibitory signals. Here, we have identified RECS1 (responsive to centrifugal force and shear stress 1) [also known as TMBIM1 (transmembrane BAX ...
    • Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells 
      Rodríguez, Diego A.; Moncada, Claudio; Núñez González, Marco; Lavandero González, Sergio; Ponnappa, Biddanda C.; Israel Jacard, Yedy (PERGAMON-ELSEVIER SCIENCE LTD, 2004-05)
      Chronic ethanol consumption leads to cell injury in virtually every tissue. Tumor necrosis factor-alpha (TNF-alpha) constitutes a major factor in the development of alcohol-induced liver injury. In alcohol-dependent subjects, ...
    • Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat 
      Rodríguez, Diego A.; Rojas Rivera, Diego; Hetz Flores, Claudio (Elsevier, 2011-04)
      The assembling of distinct signaling protein complexes at the endoplasmic reticulum (ER) membrane controls several stress responses related to calcium homeostasis. autophagy, ER morphogenesis and protein folding. Diverse ...