Browsing by Author "Rojo, Leonel"

Now showing items 1-5 of 5

    • Cognitive impairment and Alzheimer's disease: Links with oxidative stress and cholesterol metabolism 
      Sekler, Alejandra; Jiménez, José M.; Rojo, Leonel; Pastene, Edgard; Fuentes, Patricio; Slachevsky Chonchol, Andrea; Maccioni Baraona, Ricardo (BioMed Central, 2008)
      Oxidative stress has be en implicated in the progression of a number of neurodegenerative diseases, inc1uding Alzheimer's disease (AD), Parkinson's disease and amyotrophic lateral sclerosis. We carried out a~ in-depth ...
    • Cognitive impairment and Alzheimer's disease: Links with oxidative stress and cholesterol metabolism 
      Sekler, Maria Alejandra; Jiménez, José M.; Rojo, Leonel; Pastene, Edgard; Fuentes, Patricio; Slachevsky Chonchol, Andrea; Maccioni Baraona, Ricardo (2008)
      Oxidative stress has been implicated in the progression of a number of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease and amyotrophic lateral sclerosis. We carried out an in-depth study ...
    • Neuroinflammation: Implications for the pathogenesis and molecular diagnosis of Alzheimer's disease 
      Rojo, Leonel; Fernández Darraz, Jorge; Maccioni, Andrea A.; González Jiménez, José; Maccioni Baraona, Ricardo (ELSEVIER SCIENCE INC, 2007-05-31)
      During the past few years, an increasing set of evidence has supported the major role of deregulation of the interaction patterns between glial cells and neurons in the pathway toward neuronal degeneration. Neurons and ...
    • The Role of Neuroimmunomodulation in Alzheimer's Disease 
      Maccioni Baraona, Ricardo; Rojo, Leonel; Fernández, Jorge A.; Kuljis, Rodrigo O. (BLACKWELL, 2009)
      The idea that alterations in the brain immunomodulation are critical for Alzheimer’s disease (AD) pathogenesis provides the most integrative view on this cognitive disorder, considering that converging research lines ...
    • The damage signals hypothesis of Alzheimer's disease pathogenesis 
      Fernández, Jorge A.; Rojo, Leonel; Kuljis, Rodrigo O.; Maccioni Baraona, Ricardo (IOS Press, 2008)
      Virtually none of the hypotheses on Alzheimer's disease (AD) pathogenesis address the earliest events that trigger the molecular alterations that precede cerebral degeneration and account for the diversity of risk factors ...