Browsing by Author "Ruff, Marc"

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    • Intasome architecture and chromatin density modulate retroviral integration into nucleosome 
      Benleulmi, Salah S.; Matysiak, Julien; Henríquez, Rodrigo R.; Vaillant, Cédric; Lesbats, Paul; Calmels, Christina; Naughtin, Monica; León, Oscar; Skalka, Anna Marie; Ruff, Marc; Lavigne, Marc; Andreola, Marie Line; Parissi, Vincent (BioMed Central, 2015)
      Background: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by ...