Browsing by Author "Sáez, Juan C."
Now showing items 1-4 of 4
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Aguirre, Adam; Shoji, Kenji F.; Sáez, Juan C.; Henríquez Luna, Mauricio; Quest, Andrew F. G. (Wiley Periodicals, Inc., 2013)Fas ligation via the ligand FasL activates the caspase-8/caspase-3-dependent extrinsic death pathway. In so-called type II cells, an additional mechanism involving tBid-mediated caspase-9 activation is required to efficiently ...
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Mendoza Naranjo, Ariadna; Sáez, Pablo J.; Johansson, C. Christian; Ramírez Fernández, Marcos; Mandakovic Seyler, Dinka; Pereda, Cristián; López Nitsche, Mercedes; Kiessling, Rolf; Sáez, Juan C.; Salazar Onfray, Flavio (2007)Previously, we found that human dendritic cells (hDCs) pulsed with a melanoma cell lysate (MCL) and stimulated with TNF-ce (MCL/TNF) acquire a mature phenotype in vitro and are able to trigger tumor-specific immune responses ...
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Elgueta, Raúl; Tobar, Jaime A.; Shoji, Kenji F.; De Calisto, Jaime; Kalergis, Alexis M.; Bono Merino, María Rosa; Rosemblatt Silber, Mario César; Sáez, Juan C. (AMER ASSOC IMMUNOLOGISTS, 2009-04-30)The acquired immune response begins with Ag presentation by dendritic cells (DCs) to naive T cells in a heterocellular cell-cell contact-dependent process. Although both DCs and T cells are known to express connexin43, a ...
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Retamal, Mauricio Antonio; Alcayaga Urbina, Julio; Verdugo, Christian A.; Bultynck, Geert; Leybaert, Luc; Sáez, Pablo José; Fernández, Ricardo; León, Luis; Sáez, Juan C. (2014)Satellite glial cells (SGCs) are the main glia in sensory ganglia. They surround neuronal bodies and form a cap that prevents the formation of chemical or electrical synapses between neighboring neurons. SGCs have been ...