Browsing by Author "Saavedra, Kathleen"

Now showing items 1-4 of 4

    • Epigenetic mechanisms involved in cisplatin-induced nephrotoxicity: An update 
      Loren, Pía; Saavedra, Nicolás; Saavedra, Kathleen; Zambrano Coloma, Tomas Andrés; Moriel, Patricia; Salazar, Luis A. (MDPI, 2021)
      Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic regulation has emerged as a modulatory ...
    • Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor ... 
      Saavedra, Kathleen; Valbuena, José; Olivares, Wilda; Marchant, María José; Rodríguez, Andrés; Torres Estay, Verónica; Carrasco Avino, Gonzalo; Guzmán, Leda; Aguayo González, Francisco; Roa, Juan Carlos; Corvalán, Alejandro H. (Public Library Science, 2015)
      Reprimo (RPRM), a downstream effector of p53-induced cell cycle arrest at G2/M, has been proposed as a putative tumor suppressor gene (TSG) and as a potential biomarker for non-invasive detection of gastric cancer (GC). ...
    • MicroRNA-33b is a potential non-invasive biomarker for response to atorvastatin treatment in chilean subjects ... 
      Ubilla, Carmen Gloria; Prado, Yalena; Angulo, Jeremy; Obreque, Ignacio; Páez, Isis; Saavedra, Nicolás; Saavedra, Kathleen; Zambrano Coloma, Tomás Andrés; Salazar, Luis A. (Frontiers Media, 2021)
      Evidence accumulated so far indicates that circulating levels of microRNAs (miRNAs) are associated with several pathologies. Therefore, differential expression of extracellular miRNAs exhibits promising potential for ...
    • Noncoding Genomics in Gastric Cancer and the Gastric Precancerous Cascade: Pathogenesis and Biomarkers 
      Sandoval Bórquez, Alejandra; Saavedra, Kathleen; Carrasco Avino, Gonzalo; García Bloj, Benjamin; Fry, Jacqueline; Wichmann, Ignacio; Corvalán, Alejandro H. (Hindawi Publishing, 2015)
      Gastric cancer is the fifth most common cancer and the third leading cause of cancer-related death, whose patterns vary among geographical regions and ethnicities. It is a multifactorial disease, and its development depends ...