Browsing by Author "San Martín Rovirosa, Carol Dazil"

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    • Neuronal rubicon represses extracellular APP/amyloid beta deposition in Alzheimer's disease 
      Espinoza, Sandra; Grunenwald, Felipe; Gomez, Wileidy; García, Felipe; Abarzúa Catalán, Lorena; Oyarce Pezoa, Sebastián; Hernández, María Fernanda; Cortés, Bastián I.; Uhrig, Markus; Ponce de la Vega, Daniela Paz; Durán Aniotz, Claudia; Hetz Flores, Claudio Andres; San Martín Rovirosa, Carol Dazil; Cornejo Corona, Víctor Hugo; Ezquer, Fernando; Parra Ortiz, Valentina María; Behrens Pellegrino, María Isabel Ofelia; Manque, Patricio A.; Rojas Rivera, Diego; Vidal, René L.; Woehlbier, Ute; Nassif, Melissa (MDPI, 2022)
      Alzheimer's disease (AD) is the most prevalent age-associated neurodegenerative disease. A decrease in autophagy during aging contributes to brain disorders by accumulating potentially toxic substrates in neurons. Rubicon ...
    • Senescence markers in peripheral blood mononuclear cells in amnestic mild cognitive impairment and alzheimer’s ... 
      Salech Morales, Felipe Humberto; San Martín Rovirosa, Carol Dazil; Concha Cerda, Jorge Ignacio; Romero Hernández, Esteban Ignacio; Ponce, Daniela P.; Liabeuf Altamirano, Gianella Alejandra; Rogers Castillo, Nicole Andrea; Murgas, Paola; Bruna, Bárbara; More, Jamileth; Behrens Pellegrino, María Isabel (MDPI, 2022)
      Recent studies suggest that cellular senescence plays a role in Alzheimer’s Disease (AD) pathogenesis. We hypothesize that cellular senescence markers might be tracked in the peripheral tissues of AD patients. Senescence ...