Browsing by Author "Sandoval, Rodrigo"

Now showing items 1-10 of 10

    • A novel earwax self-sampling device: A feasibility study 
      Herane Vives, Andrés Rubén; Sandoval, Rodrigo; Ortega, Lorena; Espinoza, Susana; Cleare, Anthony; Hayes, Alexander; Ortúzar, Esteban; Valdenegro, Tomás; Aguiló Vidal, Bruno; Benöhr, Jan; Arnone, Danilo (MDPI, 2021)
      (1) Background: Earwax might provide the long-term concentration of substances that are altered in chronic diseases. Standardised earwax extraction has to be exclusively performed by clinicians. We investigated the safety, ...
    • Antagonistic effects of TrkB and p75(NTR) on NMDA receptor currents in post-synaptic densities transplanted ... 
      Sandoval, Mauricio; Sandoval, Rodrigo; Thomas, Ulrich; Spilker, Christina; Smalla, Karl-Heinz; Falcón, Romina; Marengo, Juan José; Calderón, Rodrigo; Saavedra, Verónica; Heumann, Rolf; Bronfman, Francisca; Garner, Craig C.; Gundelfinger, Eckart D.; Wyneken, Ursula (2007)
      Brain-derived neurotrophic factor (BDNF) and its receptor TrkB are essential regulators of synaptic function in the adult CNS. A TrkB-mediated effect at excitatory synapses is enhancement of NMDA receptor (NMDA-R)-mediated ...
    • Antagonistic effects of TrkB and p75(NTR) on NMDA receptor currents in post-synaptic densities transplanted ... 
      Sandoval, Mauricio; Sandoval, Rodrigo; Thomas, Ulrich; Spilker, Christina; Smalla, Karl-Heinz; Falcón, Romina; Marengo, Juan José; Calderón, Rodrigo; Saavedra, Verónica; Heumann, Rolf; Bronfman, Francisca; Garner, Craig C.; Gundelfinger, Eckart D.; Wyneken, Ursula (2007)
      Brain-derived neurotrophic factor (BDNF) and its receptor TrkB are essential regulators of synaptic function in the adult CNS. A TrkB-mediated effect at excitatory synapses is enhancement of NMDA receptor (NMDA-R)-mediated ...
    • Antagonistic effects of TrkB and p75NTR on NMDA receptor currents in post-synaptic densities transplanted ... 
      Sandoval, Mauricio; Sandoval, Rodrigo; Thomas, Ulrich; Spilker, Christina; Smalla, Karl-Heinz; Falcón, Romina; Marengo, Juan José; Calderón, Rodrigo; Saavedra, Verónica; Heumann, Rolf; Bronfman, Francisca; Craig C., Garner; Gundelfinger, Eckart D.; Wyneken, Úrsula (International Society for Neurochemistry, 2007)
      Brain-derived neurotrophic factor (BDNF) and its receptor TrkB are essential regulators of synaptic function in the adult CNS. A TrkB-mediated effect at excitatory synapses is enhancement of NMDA receptor (NMDA-R)-mediated ...
    • Assessing biomarkers and neuropsychological outcomes in rural populations exposed to organophosphate ... 
      Ramírez-Santana, Muriel; Zúñiga, Liliana; Corral, Sebastián; Sandoval, Rodrigo; Scheepers, Paul Tj; Van Der Velden, Koos; Roeleveld, Nel; Pancetti, Floria (BioMed Central Ltd., 2015)
      © 2015 Ramírez-Santana et al.; licensee BioMed Central. Background: Health effects of pesticides are easily diagnosed when acute poisonings occurs, nevertheless, consequences from chronic exposure can only be observed when ...
    • Assessing biomarkers and neuropsychological outcomes in rural populations exposed to organophosphate ... 
      Ramírez Santana, Muriel; Zúñiga, Liliana; Corral Zavala, Sebastián; Sandoval, Rodrigo; Scheepers, Paul; Van der Velden, Koos; Roeleveld, Nel; Pancetti, Floria (BioMed Central, 2015)
      Health effects of pesticides are easily diagnosed when acute poisonings occurs, nevertheless, consequences from chronic exposure can only be observed when neuropsychiatric, neurodegenerative or oncologic pathologies ...
    • Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair ... 
      González Gronow, Mario; Cuchacovich Turteltaub, Miguel; Francos, Rina; Cuchacovich, Stephanie; Blanco, Ángel; Sandoval, Rodrigo; Farías Gómez, Cristian; Valenzuela, Javier; Ray, Rupa; Pizzo, Salvatore (Elsevier, 2015)
      Autoantibodies from autistic spectrum disorder (ASD) patients react with multiple proteins expressed in the brain. One such autoantibody targets myelin basic protein (MBP). ASD patients have autoantibodies to MBP of both ...
    • Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent ... 
      Sandoval, Rodrigo; González, Andrés; Caviedes, Ariel; Pancetti, Floria; Smalla, Karl Heinz; Kaehne, Thilo; Michea Acevedo, Luis; Gundelfinger, Eckart D.; Wyneken, Ursula (WILEY-BLACKWELL, 2011-09)
      Nitric oxide (NO) has been proposed to down-regulate NMDA receptors (NMDA-Rs) in a homeostatic manner. However, NMDA-R-dependent NO synthesis also can cause excitotoxic cell death. Using bicuculline-stimulated hippocampal ...
    • Neurological and neuropsychological deterioration in artisanal gold miners from the town of Andacollo, Chile 
      Corral, Sebastián; Sáez, David; Lam, Gislaine; Lillo, Patricia; Sandoval, Rodrigo; Lancellotti, Domingo; Radon, Katja; Zúñiga, Liliana; Moraga, Daniel; Pancetti, Floria (2013)
      It is widely known that human exposure to mercury vapor can cause neurological and neuropsychological deterioration. We have investigated if a population of Chilean artisanal gold-mining workers heavily exposed to elemental ...
    • Protein kinase CK2 in postsynaptic densities: Phosphorylation of PSD-95/SAP90 and NMDA receptor regulation 
      Soto, Dagoberto; Pancetti, Floria; Marengo, Juan José; Sandoval, Mauricio; Sandoval, Rodrigo; Orrego, Fernando; Wyneken, Ursula (2004)
      Protein kinase CK2 (CK2) is highly expressed in rat forebrain where its function is not well understood. Subcellular distribution studies showed that the catalytic subunit of CK2 (CK2α) was enriched in postsynaptic densities ...