Browsing by Author "Santapau, Daniela"

Now showing items 1-4 of 4

    • A novel morphine drinking model of opioid dependence in rats 
      Berrios Cárcamo, Pablo; Quezada, Mauricio; Santapau, Daniela; Morales Retamales, Eugenia; Olivares, Belén; Ponce, Carolina; Ávila, Alba; Gregorio, Cristian de; Ezquer, Marcelo; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy; Ezquer, Fernando (MDPI, 2022)
      An animal model of voluntary oral morphine consumption would allow for a pre-clinical evaluation of new treatments aimed at reducing opioid intake in humans. However, the main limitation of oral morphine consumption in ...
    • Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol ... 
      Ezquer, Fernando; Morales Retamales, Paola; Quintanilla González, María Elena; Santapau, Daniela; Lespay Rebolledo, Carolyne; Ezquer, Marcelo; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Nature, 2018)
      Chronic alcohol intake leads to neuroinflammation and astrocyte dysfunction, proposed to perpetuate alcohol consumption and to promote conditioned relapse-like binge drinking. In the present study, human mesenchymal stem ...
    • NFAT5 Is Activated by Hypoxia: Role in Ischemia and Reperfusion in the Rat Kidney 
      Villanueva, Sandra; Suazo, Cristián; Santapau, Daniela; Pérez, Francisco; Quiroz, Mariana; Carreño, Juan E.; Illanes, Sebastián; Lavandero González, Sergio; Michea Acevedo, Luis; Irarrázabal, Carlos E. (Niels Olsen Saraiva Caˆmara, Universidade de Sao Paulo, Brazil, 2012)
      The current hypothesis postulates that NFAT5 activation in the kidney’s inner medulla is due to hypertonicity, resulting in cell protection. Additionally, the renal medulla is hypoxic (10–18 mmHg); however there is no ...
    • Urinary Extracellular Vesicles as a source of NGAL for diabetic kidney disease evaluation in children and ... 
      Ugarte, Francisca; Santapau, Daniela; Gallardo, Vivian; Garfias, Carolina; Yizmeyián, Anahí; Villanueva, Soledad; Sepúlveda, Carolina; Rocco, Jocelyn; Pasten, Consuelo; Urquid, Cinthya; Cavada Chacón, Gabriel Alfredo; San Martín, Pamela; Cano Schuffeneger, Francisco Javier; Irarrázaval, Carlos E. (Frontiers Media, 2022)
      Background: Tubular damage has a role in Diabetic Kidney Disease (DKD). We evaluated the early tubulointerstitial damage biomarkers in type-1 Diabetes Mellitus (T1DM) pediatric participants and studied the correlation with ...