Browsing by Author "Santibanez, Juan F."
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Santibanez, Juan F.; Blanco, Francisco J.; Garrido-Martin, Eva M.; Sanz-Rodriguez, Francisco; Del Pozo, Miguel A.; Bernabeu, Carmelo (2008)Aims: Activin receptor-like kinase (ALK)1 is a transforming growth factor (TGF)-β type I membrane receptor restricted almost entirely to endothelial cells (ECs) and involved in vascular remodelling and angiogenesis. Previous ...
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Santibanez, Juan F.; Letamendia, Ainhoa; Perez-Barriocanal, Fernando; Silvestri, Cristoforo; Saura, Marta; Vary, Calvin P.H.; Lopez-Novoa, Jose M.; Attisano, Liliana; Bernabeu, Carmelo (2007)The endothelial nitric oxide synthase (eNOS) is a critical regulator of cardiovascular homeostasis, whose dysregulation leads to different vascular pathologies. Endoglin is a component of the transforming growth factor ...
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Kocic, Jelena; Bugarski, Diana; Santibanez, Juan F. (2012)Transforming growth factor-β1 (TGF-β1) stimulates the extracellular matrix degrading proteases expression and cell migration in order to enhance cancer cells malignancy. In the present study, we analysed the role of ...
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Villar, Victor; Kocić, Jelena; Santibanez, Juan F. (2010)TGF-β1 is a potent inductor of malignance in cancer cells. TGF-β1 stimulates the expression of extracellular matrix degrading proteases, cell migration and it is also involved in the epithelial-mesenchymal transition (EMT). ...
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Santibanez, Juan F.; Pérez-Gómez, Eduardo; Fernandez-L, Africa; Garrido-Martin, Eva M.; Carnero, Amancio; Malumbres, Marcos; Vary, Calvin P.H.; Quintanilla, Miguel; Bernabéu, Carmelo (Oxford University Press, 2010)Endoglin is a coreceptor for transforming growth factor-β (TGF-β) that acts as a suppressor of malignancy during mouse skin carcinogenesis. Because in this model system H-Ras activation drives tumor initiation and progression, ...