Browsing by Author "Sardi, Sergio P."

Now showing items 1-3 of 3

    • A new model to study cell-to-cell transfer of αSynuclein in vivo 
      Mercado, Gabriela; López, Nélida; Martínez, Alexis; Sardi, Sergio P.; Hetz Flores, Claudio (Elsevier B.V., 2018)
      © 2018 Elsevier Inc. Parkinson's disease (PD) compromises motor control due to the loss of dopaminergic neurons in the substantia nigra pars compacta. At the histopathological level, PD is characterized by the accumulation ...
    • Gene Therapy Strategies to Restore ER Proteostasis in Disease 
      Valenzuela, Vicente; Jackson, Kasey L.; Sardi, Sergio P.; Hetz Flores, Claudio (Cell Press, 2018)
      © 2018 The American Society of Gene and Cell Therapy Proteostasis alterations are proposed as a transversal hallmark of several pathological conditions, including metabolic disorders, mechanical injury, cardiac malfunction, ...
    • Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of ... 
      Mercado, Gabriela; Castillo, Valentina; Soto, Paulina; López, Nélida; Axten, Jeffrey M.; Sardi, Sergio P.; Hoozemans, Jeroen J.M.; Hetz Flores, Claudio (Academic Press Inc., 2018)
      © 2018 Elsevier Inc. Parkinson's disease (PD) is the second most common neurodegenerative disorder, leading to the progressive decline of motor control due to the loss of dopaminergic neurons in the substantia nigra pars ...