Browsing by Author "Schneider, Pascal"

Now showing items 1-5 of 5

    • Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes 
      Ávalos, Ana María; Arthur, William T.; Schneider, Pascal; Quest, Andrew F. G.; Burridge, Keith; Leyton Campos, Lisette (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2004-09-10)
      Thy-1, a cell adhesion molecule abundantly expressed in mammalian neurons, binds to a beta(3)-containing integrin on astrocytes and thereby stimulates the assembly of focal adhesions and stress fibers. Such events lead to ...
    • An outside-in switch in integrin signaling caused by chemical and mechanical signals in reactive astrocytes 
      Pérez González, Leonardo; Rashid, Aysha; Combs, J. Dale; Schneider, Pascal; Rodríguez, Andrés; Salaita, Khalid; Leyton Campos, Lisette (Frontiers Media, 2021)
      Astrocyte reactivity is associated with poor repair capacity after injury to the brain, where chemical and physical changes occur in the damaged zone. Astrocyte surface proteins, such as integrins, are upregulated, and the ...
    • Direct Thy-1/alpha(V)beta(3) integrin interaction mediates neuron to astrocyte communication 
      Hermosilla, Tamara; Muñoz, Daniel; Herrera Molina, Rodrigo; Valdivia, Alejandra; Muñoz, Nicolás; Nham, Sang-Uk; Schneider, Pascal; Burridge, Keith; Quest, Andrew F. G.; Leyton Campos, Lisette (ELSEVIER, 2008-06)
      Thy-1 is an abundant neuronal glycoprotein of poorly defined function. We recently provided evidence indicating that Thy-1 clusters a beta(3)-containing integrin in astrocytes to induce tyrosine phosphorylation, RhoA ...
    • Thy-1 (CD90)-induced metastatic cancer cell migration and invasion are β3 integrin-dependent and involve a ... 
      Brenet Rivas, Marianne del Pilar; Martínez, Samuel; Pérez Núñez, Ramón; Pérez González, Leonardo Andrés; Contreras, Pamela; Díaz, Jorge; Ávalos, Ana María; Schneider, Pascal; Quest, Andrew Frederick Geoffery; Leyton Campos, Lisette (Frontiers Media, 2021)
      Cancer cell adhesion to the vascular endothelium is an important step in tumor metastasis. Thy-1 (CD90), a cell adhesion molecule expressed in activated endothelial cells, has been implicated in melanoma metastasis by ...
    • Thy-1-mediated cell–cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4 
      Kong, Milene; Muñoz, Nicolás; Valdivia, Alejandra; Álvarez, Ávaro; Herrera Molina, Rodrigo; Cárdenas, Areli; Schneider, Pascal; Burridge, Keith; Quest, Andrew F. G.; Leyton Campos, Lisette (Elsevier, 2013)
      Cell adhesion to the extracellular matrix proteins occurs through interactions with integrins that bind to Arg-Gly-Asp (RGD) tripeptides, and syndecan-4, which recognizes the heparin-binding domain of other proteins. ...