Browsing by Author "Shimahara, Takeshi"

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    • Cell lines as in vitro models for drug screening and toxicity studies 
      Allen, David D.; Caviedes Codelia, Raúl; Cárdenas, Ana María; Shimahara, Takeshi; Segura Aguilar, Juan; Caviedes Fernández, Pablo (DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2005)
      Cell culture is highly desirable, as it provides systems for ready, direct access and evaluation of tissues. The use of tissue culture is a valuable tool to study problems of clinical relevance, especially those related ...
    • Neuronal dysfunction in Down syndrome: Contribution of neuronal models in cell culture 
      Saud, Katherine; Arriagada Abarzúa, Christian; Cárdenas, Ana María; Shimahara, Takeshi; Allen, David D.; Caviedes Codelia, Raúl; Caviedes Fernández, Pablo (ELSEVIER, 2006-05)
      Down syndrome (DS) in humans, or trisomy of autosome 21, represents the hyperdiploidy that most frequently survives gestation, reaching an incidence of I in 700 live births. The condition is associated with multisystemic ...