Browsing by Author "Silva, Patricio"

Now showing items 1-9 of 9

    • Boric's Government and Its Transformative Hallmark 
      Peña González, Carlos Hernán; Silva, Patricio (Routledge, 2024)
    • Down-regulation of Rab5 decreases characteristics associated with maintenance of cell transformation 
      Silva, Patricio; Soto, Nicolás; Díaz, Jorge; Mendoza, Pablo; Díaz, Natalia; Quest, Andrew F. G.; Torres Gómez, Vicente (Elsevier, 2015)
      The early endosomal protein Rab5 is highly expressed in tumor samples, although a causal relationship between Rab5 expression and cell transformation has not been established. Here, we report the functional effects of ...
    • Probing solubilization sites in block copolymer micelles using fluorescence quenching 
      Olea, Andrés F.; Silva, Patricio; Fuentes, Irma; Martínez Concha, Francisco; Worrall, David R. (Elsevier, 2011)
      The solubilization sites provided by micelles formed by a diblock copolymer with one neutral hydrophobic block, polystyrene, and one charged hydrophilic block, poly(acrylic acid) or poly(methacrylic acid), have been ...
    • Role of glycosylation in hypoxia-driven cell migration and invasion 
      Arriagada, Cecilia; Silva, Patricio; Torres, Vicente A. (NLM (Medline), 2019)
      Hypoxia, a common condition of the tumor microenvironment, induces changes in the proteome of cancer cells, mainly via HIF-1, a transcription factor conformed by a constitutively expressed β-subunit and an oxygen-regulated ...
    • SELF-ASSEMBLY OF TRIBLOCK COPOLYMERS IN AQUEOUS SOLUTION 
      Urbano, Bruno; Silva, Patricio; Olea, Andrés F.; Fuentes, Irma; Martínez Concha, Francisco (Sociedad Chilena de Química, 2008-06)
      The aggregation of PE4VP-b-PS-b-PE4VP block copolymers was studied in aqueous solution. Triblock copolymers P4VP-b-PS-b-P4VP were synthesized by sequential anionic polymerization of poly(styrene) and poly(4-vinylpirydine) ...
    • Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy 
      Troncoso Magñin, Mayarling Francisca; Pavez Giani, Mario Gustavo; Wilson Rodríguez, Carlos Antonio; Lagos Cerón, Daniel Alejandro; Durán Gárate, Javier Andre; Ramos, Sebastián; Barrientos Briones, Genaro Christian; Silva, Patricio; Llanos Vidal, Paola Andrea; Basualto Alarcón, Carla Edith; Westenbrink, B. Daan; Lavandero González, Sergio Alejandro; Estrada Hormazábal, Manuel Iván (BMC, 2021)
      Background Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that ...
    • Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway 
      Altamirano, Francisco; Oyarce, César; Silva, Patricio; Toyos, Marcela; Wilson, Carlos; Lavandero González, Sergio; Uhlen, L.; Estrada, M. (BIOSCIENTIFICA LTD, 2009-08)
      Elevated testosterone concentrations induce cardiac hypertrophy but the molecular mechanisms are poorly understood. Anabolic properties of testosterone involve in increase in protein synthesis. The mammalian target of ...
    • The Boric Government in Chile: between refoundation and reform 
      Peña González, Carlos Hernán; Silva, Patricio (Routledge, 2024)
      This book analyses the victory of Gabriel Boric in Chile during the presidential elections of December 2021. He brought the radical left into power, after three decades of centre- left and right- wing governments. In order ...
    • The Challenges of the Boric Government 
      Peña González, Carlos Hernán; Silva, Patricio (Routledge, 2024)
      During Boric's first year in government, this agenda has remained nothing but words, forming part of his discourse as a kind of generic inspiration for what the government does, without turning this into specific public ...