Browsing by Author "Simirgiotis, Mario J."

Now showing items 1-7 of 7

    • Activity of semi-synthetic mulinanes against MDR, pre-XDR, and XDR strains of mycobacterium tuberculosis 
      Martínez González, María Alejandrina; Peña Rodríguez, Luis Manuel; Uc-Cachón, Andrés Humberto; Bórquez, Jorge; Simirgiotis, Mario J.; Barrios García, Hugo Brígido; Hernández Pando, Rogelio; Loyola, Luis Alberto; Areche Medina, Carlos Alberto; Dzul-Beh, Ángel de Jesús; Barrios Payan, Jorge Alberto; Mata Espinosa, Dulce; Escalante Erosa, Fabiola; García Sosa, Karlina; Molina Salinas, Gloria María (MDPI, 2021)
      Tuberculosis causes more than 1.2 million deaths each year. Worldwide, it is the first cause of death by a single infectious agent. The emergence of drug-resistant strains has limited pharmacological treatment of the ...
    • An unusual mulinane diterpenoid from the Chilean plant Azorella trifurcata (Gaertn) Pers 
      Areche, Carlos; Sepúlveda, Beatriz; Martin, Aurelio San; García Beltrán, Olimpo; Simirgiotis, Mario J.; Cañete, Alvaro (Royal Society of Chemistry, 2014)
      Four new mulinane-type diterpenoids besides the known compounds mulin-11,13-dien-20-oic acid, 13α-hydroxyazorellane, 13β- hydroxyazorellane, mulinolic acid, azorellanol, and mulin-11,13-dien-18-acetoxy- 16,20-dioic acid ...
    • Analysis of carotenoids in haloarchaea species from Atacama saline lakes by high resolution UHPLC-Q-Orbitrap-Mass ... 
      Lizama, Catherine; Romero Parra, Javier Hernán; Andrade, Daniel; Riveros, Felipe; Bórquez, Jorge; Ahmed, Shakeel; Venegas Salas, Luis; Cabalín, Carolina; Simirgiotis, Mario J. (MDPI, 2021)
      Haloarchaea are extreme halophilic microorganisms belonging to the domain Archaea, phylum Euryarchaeota, and are producers of interesting antioxidant carotenoid compounds. In this study, four new strains of Haloarcula sp., ...
    • Fast Detection of Phenolic Compounds in Extracts of Easter Pears (Pyrus communis) from the Atacama Desert ... 
      Simirgiotis, Mario J.; Quispe, Cristina; Borquez, Jorge; Areche Medina, Carlos; Sepúlveda, Beatriz (MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, 2016)
      A small Chilean variety of pears growing in the town of Toconao, an oasis located at the northeastern edge of the Salar de Atacama, northern Chile, was studied by means of modern PDA and high resolution mass spectral data ...
    • Seco-Taondiol, an Unusual Meroterpenoid from the Chilean Seaweed Stypopodium flabelliforme and Its ... 
      Areche Medina, Carlos; Benites, Julio; Cornejo, Alberto; Ruiz, Lina M.; García Beltrán, Olimpo; Simirgiotis, Mario J.; Sepúlveda, Beatriz (2015)
      Ten known meroterpenoids and the new meroterpenoid 7 were isolated from the Chilean seaweed Stypopodium flabelliforme as their acetylated derivatives. Furthermore, the known metabolite taondiol has been isolated for the ...
    • UHPLC-MS chemical fingerprinting and antioxidant, antiproliferative, and enzyme inhibition potential of ... 
      Fernández Galleguillos, Carlos; Quesada Romero, Luisa; Puerta, Adrián; Padrón, José M.; Souza, Ernane; Romero Parra, Javier Hernán; Simirgiotis, Mario J. (MDPI, 2021)
      Gaultheria pumila (Ericaceae) (known as Chaura or Mutilla) is a Chilean native small shrub that produces berry fruits consumed by local Mapuche people. In this study, the chemical fingerprinting and antioxidant, enzyme ...
    • UHPLC-MS metabolomic fingerprinting, antioxidant, and enzyme inhibition activities of himantormia lugubris ... 
      Areche Medina, Carlos Alberto; Romero Parra, Javier Hernán; Sepúlveda, Beatriz; García Beltrán, Olimpo; Simirgiotis, Mario J. (MDPI, 2022)
      Himantormia lugubris is a Chilean native small lichen shrub growing in the Antarctica region. In this study, the metabolite fingerprinting and the antioxidant and enzyme inhibitory potential from this species and its four ...