Browsing by Author "Torres, Gloria"

Now showing items 1-6 of 6

    • Buthionine sulfoximine has anti-Trypanosoma cruzi activity in a murine model of acute Chagas' disease and ... 
      Faúndez, Mario; López Muñoz, Rodrigo; Torres, Gloria; Morello Casté, Antonio; Ferreira, Jorge; Kemmerling Weis, Ulrike; Orellana Bown, Myriam; Maya Arango, Juan (AMER SOC MICROBIOLOGY, 2008)
      L-Buthionine (S,R)-sulfoximine (BSO) at a dose of 220 mg/kg of body weight/day showed an anti-Trypanosoma cruzi effect in infected mice, increasing their survival rate and decreasing the parasitemias and parasite burden ...
    • GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic ... 
      Morales, Pablo E.; Torres, Gloria; Sotomayor Torres, Cristian; Peña Oyarzún, Daniel; Rivera Mejías, Pablo; Paredes, Felipe; Chiong Lay, Mario (Elsevier, 2014)
      Incretin GLP-1 has important metabolic effects on several tissues, mainly through the regulation of glucose uptake and usage. One mechanism for increasing cell metabolism is modulating endoplasmic reticulum (ER)–mitochondria ...
    • Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics ... 
      Torres, Gloria; Morales, Pablo E.; García Miguel, Marina; Norambuena Soto, Ignacio; Cartes Saavedra, Benjamin; Vidal Pena, Gonzalo; Moncada Ruff, David; Sanhueza Olivares, Fernanda; San Martín, Alejandra; Chiong Lay, Mario (PERGAMON-ELSEVIER SCIENCE LTD., 2016)
      Glucagon-like peptide-1 (GLP-1) is a neuroendocrine hormone produced by gastrointestinal tract in response to food ingestion. GLP-1 plays a very important role in the glucose homeostasis by stimulating glucose-dependent ...
    • Influence of glucose metabolism on vascular smooth muscle cell proliferation 
      Chiong Lay, Mario; Morales, Pablo Esteban; Torres, Gloria; Gutiérrez, Tómas; García Nannig, Lorena; Ibacache, Mauricio; Michea Acevedo, Luis (Hans Huber, 2013)
      Diff erentiation of vascular smooth muscle cells (VSMC) is an essential process of vascular development. VSMC have biosynthetic, proliferative, and contractile roles in the vessel wall. Alterations in the diff erentiated ...
    • Protective Role of Acetylsalicylic Acid in Experimental Trypanosoma cruzi Infection: Evidence of a 15-epi- ... 
      Molina Berríos, Alfredo Enrique; Campos Estrada, Carolina; Henríquez, Natalia; Faúndez, Mario; Torres, Gloria; Castillo, Christian; Escanilla, Sebastián; Kemmerling Weis, Ulrike; Morello Casté, Antonio; López Muñoz, Rodrigo; Maya Arango, Juan (PLoS, 2013)
      Chagas’ disease, produced by Trypanosoma cruzi, affects more than 8 million people, producing approximately 10,000 deaths each year in Latin America. Migration of people from endemic regions to developed countries has ...
    • Trypanosoma cruzi: In vitro effect of aspirin with nifurtimox and benznidazole 
      López Muñoz, Rodrigo; Faúndez, Mario; Klein, Sebastián; Escanilla, Sebastián; Torres, Gloria; Lee-Liu, Dasfne; Ferrada Parker, Jorge; Kemmerling Weis, Ulrike; Orellana Bown, Myriam; Morello Casté, Antonio; Ferreira, Arturo; Maya Arango, Juan (ELSEVIER, 2010)
      Nifurtimox and benznidazole are the only active drugs against Trypanosoma cruzi; however, they have limited efficacy and severe side effects. During primoinfection, T. cruzi infected macrophages mount an antiparasitic ...