Now showing items 1-8 of 8

    • Ferrer Sacristán, Rocío (Universidad de Chile, 2007)
      La Alantoína es un producto derivado del metabolismo de las purinas, que se produce específicamente por la oxidación del Ácido Úrico. En el reino animal la excreción de Alantoína es sintetizada por varias clases, una son ...
    • Kettlun, Ana María; Leyton, Mario; Valenzuela, María Antonieta; Mancilla, Marta; Traverso Cori, A. (1992)
      Two forms of ATP-diphosphohydrolase were identified in Solanum tuberosum tuber var. Ultimus. Their hydrolytic activity ratios (ATPase/ADPase) were over 10 for form A and 1 for form B. In the potato tuber homogenate the ...
    • Vernal Astudillo, Rolando; Dutzan Muñoz, Nicolás; Chaparro, Alejandra; Puente Piccardo, Javier; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (BLACKWELL MUNKSGAARD, 2005-04)
      Background and Aims: Interleukin-17 (IL-17) is a T-cell-derived cytokine that may play an important role in the initiation or maintenance of the pro-inflammatory response and has recently been found to stimulate osteoclastic ...
    • Hernández Ríos, Emma; Valenzuela, María Antonieta; López Otin, Carlos; Alvarez, Jesús; López, José Manuel; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2006-11)
      Background: Matrix metalloproteinases (MMPs) participate in extracellular matrix degradation in physiological and pathological conditions. The available evidence suggests that MMP-13 plays a significant role in both the ...
    • Hernández Ríos, Emma; Martínez, Benjamín; Tejerina, José María; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (2007)
      Matrix metalloproteinase (MMP)-13 is a collagenase involved in extracellular matrix degradation either by its direct degradative effects or by processing bioactive substrates. The aim of this study was to determine the ...
    • Kettlun, Ana María; Espinosa, V.; García Nannig, Lorena; Valenzuela, María Antonieta (PERGAMON-ELSEVIER SCIENCE LTD, 2005-05)
      Apyrase/ATP-diphosphohydrolase hydrolyzes di- and triphosphorylated nucleosides in the presence of a bivalent ion with sequential release of orthophosphate. We performed studies of substrate specificity on homogeneous ...
    • Hernández Ríos, Emma; Sorsa, Timo; Obregón, Fabián; Tervahartiala, Taina; Valenzuela, María Antonieta; Pozo, Patricia; Dutzan Muñoz, Nicolás; Lesaffre, Emmanuel; Molas, Marek; Gamonal Aravena, Jorge Antonio (European Federation of Periodontology, 2009-12)
      Aim: Matrix metalloproteinases (MMP)-13 can initiate bone resorption and activate proMMP-9 in vitro, and both these MMPs have been widely implicated in tissue destruction associated with chronic periodontitis. We studied ...
    • Restaino Bianchi, Carmen Gloria; Chaparro, Alejandra; Valenzuela, María Antonieta; Kettlun, Ana María; Vernal Astudillo, Rolando; Silva, A.; Puente Piccardo, Javier; Jaque, M. P.; León Berríos, Rubén; Gamonal Aravena, Jorge Antonio (2007)
      OBJECTIVE: Neutrophils play a crucial role in the defense of invading bacteria by releasing biologically active molecules. The response of peripheral blood neutrophils was studied in periodontitis-affected patients and in ...