Browsing by Author "Vargas, Romina"
Now showing items 1-8 of 8
-
Causal role of oxidative stress in unfolded protein response development in the hyperthyroid state Videla Cabrera, Luis; Fernández Arancibia, Virginia; Cornejo, Pamela; Vargas, Romina; Carrasco, Juan; Fernández, Javier; Varela Figueroa, Nelson (Elsevier, 2015)L-3,3',5-Triiodothyronine (T-3) induced liver oxidative stress underlies significant protein oxidation, which may trigger the unfolded protein response (UPR). Administration of daily doses of 0.1 mg T-3 for three consecutive ...
-
Videla Cabrera, Luis; Fernández Arancibia, Virginia; Cornejo, Pamela; Vargas, Romina (2012)The liver is a major organ responsible for most functions of cellular metabolism and a mediator between dietary and endogenous sources of energy for extrahepatic tissues. In this context, adenosine-monophosphate- (AMP-) ...
-
Zúñiga, Jessica; Cancino, Milena; Medina, Fernando; Varela, Patricia; Vargas, Romina; Tapia Opazo, Gladys; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2011)Dietary supplementation with the n-3 polyunsaturated fatty acids (n-3 PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to rats preconditions the liver against ischemia-reperfusion (IR) injury, with reduction ...
-
Morales, Paula; Vargas, Romina; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2014)Sub-chronic iron (Fe) administration induces liver oxidative stress upregulating cytoprotective mechanisms that may involve redox-sensitive nuclear factor erythroid 2-related factor 2 (Nrf2). We aimed to investigate whether ...
-
Fernández Arancibia, Virginia; Vargas, Romina; Castillo, Valentina; Cádiz, Nicolás; Bastías, Daniela; Román, Sebastián; Tapia Opazo, Gladys; Videla Cabrera, Luis (Hindawi, 2013)The role of iron (Fe)-induced prooxidant status in Fe preconditioning against ischemia (1 h)-reperfusion (20 h) induced liver injury was assessed using N-acetylcysteine (NAC) (1 g/kg) before Fe (50mg/kg), given to male ...
-
Videla Cabrera, Luis; Fernández Arancibia, Virginia; Cornejo, Pamela; Vargas, Romina; Castillo Montecinos, Iván (Cambridge University Press, 2015)Thyroid hormone (TH) exerts important actions on cellular energy metabolism, accelerating O-2 consumption with consequent reactive oxygen species (ROS) generation and redox signalling affording cell protection, a response ...
-
Videla Cabrera, Luis; Vargas, Romina; Riquelme, Barbara; Fernández, Javier; Fernández Arancibia, Virginia (Johann Ambrosius Barth Verlag Medizinverlage Heidelberg GMBH, 2018)Thyroid hormone (3,3', 5-triiodothyronine, T-3) accelerates energy metabolism in the liver through mechanisms involving upregulation of AMP-activated protein kinase (AMPK). This study aims to assess the influence of T-3 ...
-
Videla Cabrera, Luis; Cornejo, Pamela; Romanque, Pamela; Santibáñez, Catherine; Castillo, Iván; Vargas, Romina (2012)L-3,3′,5-triiodothyronine (T3) administration upregulates nuclear factor-E2-related factor 2 (Nrf2) in rat liver, which is redox-sensitive transcription factor mediating cytoprotection. In this work, we studied the role ...