Browsing by Author "Vega Blanco, María Margarita"
Now showing items 1-20 of 34
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Villavicencio, A.; Bacallao, Ketty; Avellaira, C.; Gabler Neale, Fernando; Fuentes, A.; Vega Blanco, María Margarita (2006)Objective.: To study if the endocrinological status of PCOS women affects the endometrial sensitivity to steroids by evaluating the expression of androgen receptor (AR), estrogen receptor α (ERα), estrogen receptor β (ERβ), ...
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Johnson Pena, María Cecilia; Torres, Marisa; Alves, Alejandra; Bacallao, Ketty; Fuentes García, Frans; Vega Blanco, María Margarita; Boric Scarpa, María Angélica (BIOMED CENTRAL LTD, 2005-09-08)Background: Endometriosis is a common gynaecological disorder characterized by the presence of endometrial tissue outside of the uterus. The fragments in normal menstruation are composed of necrotic and living cells, which ...
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Fornes, Romina; Ormazábal Leiva, Paulina Fernanda; Rosas, Carlos; Gabler Neale, Fernando; Vantman Bretschneider, David; Romero Osses, Carmen; Vega Blanco, María Margarita (2010-04)Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder associated with insulin resistance and compensatory hyperinsulinemia. Scarce information is available on the expression of molecules involved in the ...
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Plaza, F.; Gabler Neale, Fernando; Romero Osses, Carmen; Vantman Bretschneider, David; Valladares Boasi, Luis; Vega Blanco, María Margarita (ELSEVIER, 2010-12)The changes in endometrial homeostasis found in women with polycystic ovarian syndrome (PCOS) could be associated with alterations in the intracrine metabolism of steroid hormones. The uptake of dehydroepiandrosterone-sulphate ...
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Ormazábal Leiva, Paulina Fernanda; Romero Osses, Carmen; Gabler Neale, Fernando; Quest, Andrew F. G.; Vega Blanco, María Margarita (2013)Endometrial tissue of patients with polycystic ovary syndrome (PCOS) shows an impaired expression of insulin signaling molecules. Tyrosine phosphorylation of the insulin receptor (IR) by insulin promotes glucose uptake by ...
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Palomino Avilés, Wilder; Fuentes García, Frans; González, Rubén René; Gabler Neale, Fernando; Boric Scarpa, María Angélica; Vega Blanco, María Margarita; Devoto, Luigi (ELSEVIER, 2005-03)\Objective: To assess the effect of clomiphene citrate (CC) on endometrial epithelial integrins and P receptors (PR) during the window of implantation. Design: Controlled, prospective, clinical study. Setting: Teaching ...
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Carrasco, I.; Troncoso, J. L.; Devoto, Luigi; Vega Blanco, María Margarita (Oxford University, 1996)The differentia] capacity for steroid synthesis of human luteal cell subpopulations was investigated in a well defined cell culture system. Corpora lutea were enzymatically dissociated, and the two cell types were ...
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Astorga Leiva, Isis Paulina (Universidad de Chile, 2018)
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Oróstica Arévalo, María Lorena; García, Paula; Vera, Carolina; García, Victor; Romero Osses, Carmen; Vega Blanco, María Margarita (Sage, 2018)Polycystic ovary syndrome (PCOS) affects not only ovarian functions but is also able to affect endometrium metabolism. Around 80% of women with PCOS are obese. High tumor necrosis factor (TNF)- production and low adiponectin ...
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García, V.; Oróstica Arévalo, María Lorena; Poblete, C.; Rosas, C.; Astorga, I.; Romero Osses, Carmen; Vega Blanco, María Margarita (Georg Thieme Verlag, 2015)Hyperandrogenemia, hyperinsulinemia, and obesity affect 60-70% of patients with Polycystic Ovarian Syndrome (PCOS), who exhibit an altered endometrial insulin signaling. The aim of the study was to evaluate whether ...
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Díaz Valdivia, Natalia; Bravo, Denisse; Huerta, Hernán; Henríquez, Soledad; Gabler Neale, Fernando; Vega Blanco, María Margarita; Romero Osses, Carmen; Calderón, Claudia; Owen, Gareth I.; Leyton Campos, Lisette; Quest, Andrew F. G. (BioMed Central, 2015)Background: Caveolin-1 (CAV1) has been implicated both in tumor suppression and progression, whereby the specific role appears to be context dependent. Endometrial cancer is one of the most common malignancies of the female ...
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Ormazábal, Paulina; Romero Osses, Carmen; Gabler Neale, Fernando; Quest, Andrew F. G.; Vega Blanco, María Margarita (2013)
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Ormazábal Leiva, Paulina Fernanda (Universidad de Chile, 2011)El Síndrome de Ovario Poliquístico (SOP) es un desorden hiperandrogénico caracterizado en un 70% de los casos por insulinoresistencia con la consiguiente hiperinsulinemia compensatoria. Existen claras evidencias que indican ...
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Quezada, Susana; Avellaira, Carla; Johnson Pena, María Cecilia; Gabler Neale, Fernando; Fuentes García, Frans; Vega Blanco, María Margarita (ELSEVIER, 2006-04)Objective: To evaluate gene and protein expression of steroid receptors, nuclear receptor coregulators, and uterine receptivity markers in midsecretory phase endometria from untreated women with polycystic ovary syndrome ...
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Avellaira, C.; Villavicencio, A.; Bacallao, Ketty; Gabler Neale, Fernando; Wells, P.; Romero Osses, Carmen; Vega Blanco, María Margarita (Oxford University Press, 2006)Background: The hormonal alterations observed in women with polycystic ovary syndrome (PCOS) may promote implantation failure as well as disruption of their endometrial homeostasis. To evaluate cell survival of mid-secretory ...
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Plaza Parrochia, Francisca; Poblete, Cristian; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2015)Intracrinology mechanism involves the metabolism of steroids in peripheral tissues, such as DHEA, to molecules with estrogenic or androgenic activity. Proliferation rate of endometria from Polycystic Ovary Syndrome women ...
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Cortínez Castro, Armando; De Carvalho, Iara; Vantman Bretschneider, David; Gabler Neale, Fernando; Iñíguez Vila, Germán; Vega Blanco, María Margarita (ELSEVIER SCIENCE INC, 2005-01)Objective: To evaluate the clinical response and endometrial morphology during the implantation window on ovarian hyperstimulation with the aromatase inhibitor letrozole in infertile ovulatory women. Design: Prospective ...
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Bacallao, Ketty; León, L.; Gabler Neale, Fernando; Soto, E.; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (PERGAMON-ELSEVIER SCIENCE LTD, 2008-05)The aim of the present investigation was to study whether the endocrinological status of women bearing polycystic ovarian syndrome (PCOS) affects the endometrial in situ steroid metabolism. For this purpose, we evaluated ...
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Bacallao, Ketty; Plaza Parrochia, Francisca; Cerda, A.; Gabler Neale, Fernando; Romero Osses, Carmen; Vantman Bretschneider, David; Vega Blanco, María Margarita (SAGE, 2016)Polycystic ovarian syndrome (PCOS) has been associated with endometrial hyperplasia and cancer. The aim of this study was to establish whether the expression of proliferation regulatory proteins in the endometria of ...
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Rosas, Carlos; Kohan Ivani, Karla; Gabler Neale, Fernando; Vantman Bretschneider, David; Romero Osses, Carmen; Vega Blanco, María Margarita; Carvajal Gavilán, Rodrigo (Oxford University Press, 2013)study question: Does treatment with the insulin sensitizer metformin modify the levels and activation of proteins related to the expression of the insulin-dependent glucose transporter (GLUT4), such as adenosine ...